Aesthetic Plastic Surgery

, Volume 35, Issue 5, pp 703–708 | Cite as

Large-Breast Reconstruction Using Fat Graft Only after Prosthetic Reconstruction Failure

  • Pietro Panettiere
  • Danilo Accorsi
  • Lucio Marchetti
  • Federica Sgrò
  • Andrea Sbarbati
Original Article



When prosthetic reconstruction fails, and in the case of absolute contraindications to flaps use, no common reconstructive option is available.


A large irradiated breast was reconstructed using only fat grafts (9 sessions) after prosthetic reconstruction failure (exposure of implant) due to absolute contraindications to general anesthesia and unavailability of large flaps. During the first four sessions small volumes were implanted in the extremely rigid and retracted tissues with regenerative purposes. Larger volumes were implanted during the last five sessions to improve volume and shape.


A pleasant aesthetic result was achieved. Tissue regeneration with good vascular support was evident at ultrasonography and magnetic resonance. Histologic and ultrastructural examination of the new tissue showed normal adipose tissue with cell and vasculostromal maturation aspects. No degenerative or inflammatory aspects were present.


Fat graft transplantation can be a reliable and safe option for breast reconstruction in selected patients.


Fat graft Breast reconstruction Radiotherapy Tissue regeneration Autologous 


Conflict of interest



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Copyright information

© Springer Science+Business Media, LLC and International Society of Aesthetic Plastic Surgery 2011

Authors and Affiliations

  • Pietro Panettiere
    • 1
    • 4
  • Danilo Accorsi
    • 2
  • Lucio Marchetti
    • 2
  • Federica Sgrò
    • 2
  • Andrea Sbarbati
    • 3
  1. 1.Department of Specialistic Surgical and Anesthesiologic SciencesUniversità degli Studi di BolognaBolognaItaly
  2. 2.Villalba Hospital, VMC Gruppo Villa MariaBolognaItaly
  3. 3.Department of Neurological, Neuropsychological, Morphological and Motor Sciences, Human Anatomy and Histology SectionUniversity of VeronaVeronaItaly
  4. 4.Poliambulatorio Privato dott. Pietro PanettiereBolognaItaly

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