DRD4 gene polymorphism in great tits: gender-specific association with behavioural variation in the wild
Recent studies indicate that polymorphisms of the DRD4 gene may be related to behavioural variation in mammals and birds. The purpose of this study was to ascertain a connection between DRD4 genotypes and behavioural patterns in a wild passerine bird during breeding time. We evaluated changes in birds’ parental provisioning behaviour in the presence of a novel object. As a behavioural trait, we measured the duration of feeding interruption from the first time that each bird noticed the novel object until they entered the nest box. We found a gender-specific association between DRD4 gene polymorphism and parental behaviour. Males with a CC genotype delayed feeding for a longer period than those with CT and TT genotypes. No significant effect of genotype on provisioning behaviour was observed among females. We conclude that (i) DRD4 gene polymorphism in wild birds can be associated with behaviour related to fearfulness, and (ii) this effect is supposedly gender-specific during the breeding time, potentially explained by sex differences in parental care or hormonal levels.
KeywordsGreat tit Personality variation DRD4 gene Gender-specific association
The authors thank Kaarin Koosa for help with fieldwork, Jaanis Lodjak for help with data analysis, and Raivo Mänd and anonymous reviewers for their constructive comments. This study was financed by an Estonian Science Fund grant ETF8376 from the Ministry of Science and Education Target-Financing project no. 01800004 s09, the European Regional Development Fund (Centre of Excellence FIBIR) and from an Institutional Research grant no. IUT 34-8.
The experiments comply with the current laws of Estonia, specified in text.
- Ebstein RP, Benjamin J, Belmaker RH (2000) Genetics of personality dimensions. Curr Opin Psychiatr 13:617–622Google Scholar
- El-Faddagh M, Laucht M, Maras A, Vöhringer L, Schmidt M (2004) Association of dopamine D4 receptor (DRD4) gene with attention-deficit/hyperactivity disorder (ADHD) in a high-risk community sample: a longitudinal study from birth to 11 years of age. J Neural Transm 111:883–889CrossRefPubMedGoogle Scholar
- Queller DC (1997) Why do females care more than males? Proc R Soc Lond B 264:1555–1557Google Scholar
- van Oers K, de Jong G, van Noordwijk AJ, Kempenaers B, Drent PJ (2005) Contribution of genetics to the study of animal personalities: a review of case studies. Behaviour 142:9–10Google Scholar
- van Oers K, Drent PJ, de Goede P, van Noordwijk AJ (2004a) Realized heritability and repeatability of risk-taking behaviour in relation to avian personalities. Proc R Soc Lond B 271:65–73Google Scholar
- van Oers K, Drent PJ, de Jong G, van Noordwijk AJ (2004b) Additive and nonadditive genetic variation in avian personality traits. Heredity 93:496–503Google Scholar
- van Oers K, Mueller JC (2010) Evolutionary genomics of animal personality. Philos T Roy Soc B 365:3991–4000Google Scholar