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Cell therapy for intervertebral disc herniation and degenerative disc disease: clinical trials

  • Jordy ScholEmail author
  • Daisuke SakaiEmail author
Review
  • 107 Downloads

Abstract

Low back pain is the primary cause of disability and is highly associated with progression of intervertebral disc degeneration. Current treatment options are limited and fail to address the origin of the problem. New advancements in cellular therapies might offer novel and potent strategies for low back pain patients. In this review, we summarize and discuss the contemporary status of in-human trials investigating cellular transplantation for treatment of low back pain. We aim to highlight current trends, shortcomings, and hurdles for effective clinical trials and consecutive commercialization.

Keywords

Clinical trials Cell therapy Regenerative medicine Intervertebral disc Degeneration 

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© SICOT aisbl 2018

Authors and Affiliations

  1. 1.Department for Orthopaedic SurgeryTokai University School of MedicineIseharaJapan

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