International Orthopaedics

, Volume 34, Issue 6, pp 819–825 | Cite as

Treatment of osteochondritis dissecans of the femoral condyle with autologous bone grafts and matrix-supported autologous chondrocytes

  • Joern Steinhagen
  • Juergen Bruns
  • Georg Deuretzbacher
  • Wolfgang Ruether
  • Martin Fuerst
  • Oliver Niggemeyer
Original Paper
First Online:
Received:
Revised:
Accepted:

Abstract

The objective of this study was to determine the clinical outcome of combined bone grafting and matrix-supported autologous chondrocyte transplantation in patients with osteochondritis dissecans of the knee. Between January 2003 and March 2005, 21 patients (mean age 29.33 years) with symptomatic osteochondritis dissecans (OCD) of the medial or lateral condyle (grade III or IV) of the knee underwent reconstruction of the joint surface by autologous bone grafts and matrix-supported autologous chondrocyte transplantation. Patients were followed up at three, six, 12 and 36 months to determine outcomes by clinical evaluation based on Lysholm score, IKDC and ICRS score. Clinical results showed a significant improvement of Lysholm-score and IKDC score. With respect to clinical assessment, 18 of 21 patients showed good or excellent results 36 months postoperatively. Our study suggests that treatment of OCD with autologous bone grafts and matrix-supported autologous chondrocytes is a possible alternative to osteochondral cylinder transfer or conventional ACT.

Keywords

Subchondral Bone Defect Size Lysholm Score Osteochondral Defect Autologous Bone Graft 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Joern Steinhagen
    • 1
  • Juergen Bruns
    • 1
  • Georg Deuretzbacher
    • 1
  • Wolfgang Ruether
    • 1
  • Martin Fuerst
    • 2
  • Oliver Niggemeyer
    • 2
  1. 1.Department of OrthopaedicsUniversity of HamburgHamburgGermany
  2. 2.Department of OrthopaedicsKlinikum Bad BramstedtBad BramstedtGermany

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