Cancer immunotherapy achieves breakthrough status: 12th annual meeting of the association for cancer immunotherapy (CIMT), Mainz, Germany, May 6–8, 2014
In December 2013, the Science magazine has designated cancer immunotherapy (CIMT) as the breakthrough of the year mainly due to clinical success stories in the area of checkpoint inhibitory antibodies and cellular gene therapy. This year’s CIMT 2014 meeting covered these recent success stories as well as additional technologies and therapeutic concepts that may form the base for the next wave of innovation to reach patients in the near future. Reflecting the increasing attention the field is attracting, the annual meeting of the Association for CIMT could observe yet another rise in the number of international participants (n = 950). A total of 85 used the opportunity to give lectures and 321 presented their cutting-edge innovations in poster sessions. CIMT offered a sizable stage for the dissemination and intensive discussion of research and development efforts in the areas of tumor vaccination, combination therapy, tumor microenvironment, immunoguiding,...
KeywordsCIMT 2014 Cancer immunotherapy Cancer immunology Tumor vaccination
Adoptive cellular transfer
Antibody-dependent cellular cytotoxicity
Chimeric antigen receptor
Association for Cancer Immunotherapy
CIMT Immunoguiding Program
Cytotoxic T-lymphocyte-associated protein 4
Cytotoxic T lymphocytes
DNAX Accessory Molecule-1
Incomplete Freud’s adjuvant
Programmed cell death 1
Programmed death-ligand 1
CIMT Regulatory Research group
T effector cells
TCR-engineered reference samples
T cell immunoreceptor with Ig and ITIM domains
T regulatory cells
Vascular endothelial growth factor A
The authors would like to thank Christiane Wellié-Reeve (Mainz, Germany) for carefully proof reading the meeting report. Selected sessions of the CIMT meeting were made possible by research grants from the German Bundesministerium für Bildung and Forschung (BMBF Grant: 031A018). The CIMT working group CIP receives support for educational activities by the Wallace Coulter Foundation (Florida, USA).
Conflict of interest
The authors declare that they have no conflict of interest. Cedrik M. Britten has been the co-organizer of the meeting. Björn-Philipp Kloke has been the co-organizer of the CIMT Endeavour workshop.