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Cancer Immunology, Immunotherapy

, Volume 58, Issue 5, pp 777–787 | Cite as

Report on the sixth annual meeting of the Association for Immunotherapy of Cancer (CIMT), May 15 and 16, 2008 in Mainz, Germany

  • Marij J. P. Welters
  • Nadine van Montfoort
  • Selina Khan
  • Ralf G. Meyer
  • Cedrik M. Britten
Meeting Report
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Introduction

After one visit to Würzburg in 2007 the sixth annual meeting of the Association for Immunotherapy of Cancer (CIMT) was organized again in Mainz on May 15 and 16, 2008. More than 350 participants attended the scientific sessions with program topics ranging from fundamental research on antigen processing and mechanisms of breaking tolerance to more translational studies on adoptive T-cell transfer, vaccination and the use of adjuvants or immunomodulating agents. In addition, an extra session was organized which focused on the monitoring of immunotherapy-induced immune responses. Selected posters were discussed in short presentations during three parallel sessions. This year’s meeting provided the attendees with a comprehensive overview of the most prominent work in the field. It proved to be a very interesting and stimulating meeting, with plenty of opportunity to “meet the expert”. In contrast to prior CIMT meetings, in which the great majority of participants came from...

Keywords

Major Histocompatibility Complex Class Ipilimumab Early Endosome Transporter Associate With Antigen Processing Bispecific Antibody 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

AML

Acute myeloid leukaemia

APCs

Antigen presenting cells

CFSE

Carboxyfluorescein succinimidyl ester

CTLA-4

Cytotoxic T-lymphocyte antigen 4

DCs

Dendritic cells

DT

Diphtheria toxin

EP

Electroporation

ER

Endoplasmatic reticulum

Erb2

Estrogen receptor b2

FrC-DOM

Fragment C of tetanus toxin

GML

Genetically modified lymphocytes

GM-CSF

Granulocyte monocyte colony stimulating factor

GVHD

Graft-versus-host disease

GVL

Graft-versus-leukemia

HEL

Hen egg lysosyme

HIV

Human Immunodeficiency Virus

HSV

Herpes Simplex Virus

HLA

Human leukocyte antigen

HPV

Human papillomavirus

ICAM-1

Intercellular adhesion molecule 1

IFNγ

Interferon gamma

IL

Interleukin

i.m.

Intramuscular

KO

Knockout

MHC

Major histocompatibility complex

NIH

National Institutes of Health

NK

Natural killer

ONTAK

Denileukin-diftitox

OVA

Ovalbumin

ORP1L

Oxysterol-binding protein homologue

pMHC

Peptide–MHC complexes

RHAMM

Receptor for hyaluronic acid mediated motility

PMSA27

Prostate specific membrane antigen peptide 27

RILP

Rab-interacting lysosomal protein

TK

Thymidine kinase

Tregs

Regulatory T cells

TCR

T-cell receptor

TLR

Toll like receptor

TAP

Transporter associated with antigen processing

TNFα

Tumor necrosis factor alpha

VEGF

Vascular endothelial growth factor

Notes

Acknowledgments

The authors would like to thank Dr. A. Mander (Southampton, UK) for carefully proof reading the meeting report. C.M. Britten was funded by Dr. Mildred Scheelgrant from Deutsche Krebshilfe (German Cancer Aid).

Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • Marij J. P. Welters
    • 1
  • Nadine van Montfoort
    • 1
  • Selina Khan
    • 1
  • Ralf G. Meyer
    • 2
  • Cedrik M. Britten
    • 1
  1. 1.Department of Immunohematology and Blood TransfusionLeiden University Medical CenterLeidenThe Netherlands
  2. 2.Department of Hematology and OncologyJohannes Gutenberg-UniversityMainzGermany

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