Cancer Immunology, Immunotherapy

, Volume 56, Issue 1, pp 70–80 | Cite as

The role of CD4+ T cell help in cancer immunity and the formulation of novel cancer vaccines

  • Deepak P. Assudani
  • Roger B. V. Horton
  • Morgan G. Mathieu
  • Stephanie E. B. McArdle
  • Robert C. ReesEmail author
Symposium Paper


Recent years have seen the unprecedented surge of interest in the role of CD4+ T cells and the role they play in the development of the immune response. In this symposium review, we examine the evidence for this and discuss their functions, particularly in respect to the cancer immunology, including CD4+CD25+ cells (Treg).


Dendritic Cell Activation Induce Cell Death Restricted Peptide CT26 Tumour Cell Loaded Dendritic Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • Deepak P. Assudani
    • 1
  • Roger B. V. Horton
    • 1
  • Morgan G. Mathieu
    • 1
  • Stephanie E. B. McArdle
    • 1
  • Robert C. Rees
    • 1
    Email author
  1. 1.School of Biomedical and Natural SciencesNottingham Trent UniversityNottinghamUK

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