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Clinical significance of isolated abnormal intestinal findings in magnetic resonance enterography in patients with suspected small bowel disease

  • Yesim Ozen Alahdab
  • Coskun Ozer DemirtasEmail author
  • Haluk Tarik Kani
  • Davut Tuney
  • Lamia Seker
  • Tugba Tolu
  • Ozlen Atug
Hollow Organ GI
  • 11 Downloads

Abstract

Purpose

Magnetic resonance imaging (MRE) is a well-established adjunct diagnostic tool for the diagnosis of Crohn’s Disease (CD), as ileocolonoscopy can sometimes be falsely reassuring when CD skips distal terminal ileum. We aimed to determine the frequency and clinical significance of isolated abnormal small bowel findings in MRE with normal ileal view in ileoscopy.

Methods

We retrospectively reviewed findings from 1611 MRE studies that were conducted between 2012 and 2018 to detect patients bearing abnormal intestinal findings and having full ileocolonoscopy. After exclusion of normal or repetitive MRE scans and previously known CD, 147 patients with abnormal MRE detected. MRE scans were categorized as suspicious of CD and non-specific findings.

Results

Out of 147 patients with abnormal MRE, 122 (83%) had terminal ileum involvement in MRE consistent with ileoscopy findings. Twenty-five (17%) patients were found to have solitarily abnormal intestinal findings in MRE with normal ileoscopy. Only 3 (12%) were diagnosed with CD initially, and all had MRE findings suspicious of CD. The remainder 40% (n = 10) were diagnosed with non-Crohn’s small bowel disease after further investigation, while in the other 48% (n = 12) abnormal MRE findings could not be explained with any organic disease in the follow-up.

Conclusion

The present study demonstrated that only a small portion of patients with isolated abnormal intestinal findings in MRE is CD, and more than that are non-crohn’s small bowel diseases. These findings, even if they carry the suspicion of CD, do not transform to CD in the long-term follow-up.

Keywords

Magnetic resonance enterography Crohn’s disease Small bowel disease Ileocolonoscpy 

Notes

Funding

None.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

The study was approved by the local ethics committee of Marmara University, School of Medicine (Approval Date: 14.12.2018, Approval Number: 09.2018.789).

Informed consent

Informed consent was not obtained as this was a retrospective study.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of GastroenterologyMarmara University, School of MedicineIstanbulTurkey
  2. 2.Department of RadiologyMarmara University, School of MedicineIstanbulTurkey
  3. 3.Department of Internal MedicineMarmara University, School of MedicineIstanbulTurkey

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