Abdominal Radiology

, Volume 44, Issue 9, pp 3195–3199 | Cite as

Application of side-hole catheter technique for transradial arterial chemoembolization in patients with hepatocellular carcinoma

  • Xiao-Xi Meng
  • Hua-Qiang Liao
  • Hong-Chao Liu
  • Hai-Lin Jiang
  • Ya-Feng Gu
  • Xi Li
  • Wei-Hua DongEmail author
Interventional Radiology



The purpose of this study was to retrospectively evaluate the efficacy and safety of side-hole catheter technique for transarterial chemoembolization (TACE) via transradial artery access (TRA) in patients with hepatocellular carcinoma.

Materials and methods

From November 2015 to August 2017, a total of 1040 TACE procedures were performed via TRA for hepatocellular carcinoma. In 10 (1%) of these 1040 TACE procedures via TRA, conventional microcatheter technique (CMT) failed and side-hole catheter technique was attempted.


Ten procedures of selective catheterizations by CMT failed due to the poor stability of the angiographic catheters or the target artery arising from the very proximal portion of the parent artery. These arteries included the right inferior phrenic artery in eight patients, one left gastric artery, and one right renal capsular artery. Cobra or MPA catheter with the microcatheter through the side-hole yielded a technical success rate of 100%. No procedure-related complications were observed. The mean time required to catheterize the target artery with the side-hole catheter was 9.5 min (5–15 min).


Side-hole catheter technique may enable the completion of chemoembolization in cases that a potential tumor-feeding vessel cannot be catheterized by means of CMT for TACE via TRA.


Chemoembolization Therapeutic Carcinoma Hepatocellular Radial artery Femoral artery Catheters 



  1. 1.
    Yamada R, Bracewell S, Bassaco B, Camacho J, Anderson MB, Conrad A, Lynn C, Burns P, Collins H, Guimaraes M (2018) Transradial Versus Transfemoral Arterial Access in Liver Cancer Embolization: Randomized Trial to Assess Patient Satisfaction. Journal of vascular and interventional radiology: JVIR 29 (1):38-43. CrossRefGoogle Scholar
  2. 2.
    Yamashita T, Imai S, Tamada T, Yamamoto A, Egashira N, Watanabe S, Higashi H, Gyoten M (2007) Transradial approach for noncoronary angiography and interventions. Catheter Cardiovasc Interv 70 (2):303-308. CrossRefGoogle Scholar
  3. 3.
    Shiozawa S, Tsuchiya A, Endo S, Kato H, Katsube T, Kumazawa K, Naritaka Y, Ogawa K (2003) Transradial approach for transcatheter arterial chemoembolization in patients with hepatocellular carcinoma: comparison with conventional transfemoral approach. J Clin Gastroenterol 37 (5):412-417CrossRefGoogle Scholar
  4. 4.
    Hung ML, Lee EW, McWilliams JP, Padia SA, Ding P, Kee ST (2018) A reality check in transradial access: a single-centre comparison of transradial and transfemoral access for abdominal and peripheral intervention. Eur Radiol.
  5. 5.
    Lencioni R, de Baere T, Burrel M, Caridi JG, Lammer J, Malagari K, Martin RC, O’Grady E, Real MI, Vogl TJ, Watkinson A, Geschwind JF (2012) Transcatheter treatment of hepatocellular carcinoma with Doxorubicin-loaded DC Bead (DEBDOX): technical recommendations. Cardiovasc Intervent Radiol 35 (5):980-985. CrossRefGoogle Scholar
  6. 6.
    Miyayama S, Matsui O, Akakura Y, Yamamoto T, Fujinaga Y, Koda W, Kawai K, Notsumata K, Toya D, Tanaka N (2001) Use of a Catheter with a Large Side Hole for Selective Catheterization of the Inferior Phrenic Artery. Journal of Vascular and Interventional Radiology 12 (4):497-499. CrossRefGoogle Scholar
  7. 7.
    Oh JS, Choi BG, Chun HJ, Lee HG (2016) A side-hole catheter for catheterization of a difficult internal mammary artery. Acta Radiologica 58 (3):307-310. CrossRefGoogle Scholar
  8. 8.
    Won JH, Park SI, Park KJ, Oh YJ, Hwang SC (2004) Microcatheter placement through a side hole created in a 5-F catheter into proximal subclavian arterial branches causing hemoptysis. Journal of vascular and interventional radiology: JVIR 15 (8):881-884. CrossRefGoogle Scholar
  9. 9.
    Radner S (1948) Thoracal aortography by catheterization from the radial artery; preliminary report of a new technique. Acta radiol 29 (2):178-180CrossRefGoogle Scholar
  10. 10.
    Chung JW, Park JH, Han JK, Choi BI, Kim TK, Han MC (1998) Transcatheter oily chemoembolization of the inferior phrenic artery in hepatocellular carcinoma: the safety and potential therapeutic role. Journal of vascular and interventional radiology: JVIR 9 (3):495-500CrossRefGoogle Scholar
  11. 11.
    Kim HC, Chung JW (2014) Shepherd’s hook technique for superselective catheterization of hepatic arteries. Journal of vascular and interventional radiology: JVIR 25 (12):1993-1996. CrossRefGoogle Scholar
  12. 12.
    Kiyosue H, Matsumoto S, Hori Y, Okahara M, Sagara Y, Mori H (2004) Turn-back technique with use of a shaped microcatheter for superselective catheterization of arteries originating at acute angles. Journal of vascular and interventional radiology: JVIR 15 (6):641-643CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Xiao-Xi Meng
    • 1
  • Hua-Qiang Liao
    • 1
  • Hong-Chao Liu
    • 1
  • Hai-Lin Jiang
    • 1
  • Ya-Feng Gu
    • 1
  • Xi Li
    • 1
  • Wei-Hua Dong
    • 1
    Email author
  1. 1.Department of Interventional Radiology, Changzheng HospitalThe Second Military Medical UniversityShanghaiChina

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