Abdominal Radiology

, Volume 44, Issue 1, pp 292–303 | Cite as

Indirect percutaneous core needle biopsy of solid pancreatic or peripancreatic lesions

  • Po-Ting Chen
  • Kao-Lang LiuEmail author
  • Tsu-Yao Cheng
  • Chin-Chen Chang
  • Yeun-Chung Chang
Pictorial essay


Solid pancreatic or peripancreatic lesions comprise a heterogeneous group of diseases that rely on a multimodality imaging approach for subsequent tissue procurement. Endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA)/biopsy is an effective and safe method for tissue diagnosis in this region. The failure to obtain adequate tissue for diagnosis under EUS guidance is still a rare but important issue. Percutaneous core needle biopsy (CNB) provides an alternative pathway for adequate specimen acquisition. Because of the deep retroperitoneal location, the percutaneous biopsy of pancreatic or peripancreatic lesions may inevitably pass through visceral organs. The procedure is relatively risky and difficult for general radiologists, particularly beginners, and an adequate knowledge of the abdominal anatomy and biopsy technique is indispensable. In this review, various aspects of percutaneous CNB for solid pancreatic or peripancreatic lesions using different trans-organ approaches are reviewed to increase the chance of successful biopsy.


Biopsy Pancreas Indirect access Computed tomography Ultrasonography 


Compliance with ethical standards

Finanical support


Conflict of interest

All authors declared that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Medical ImagingNational Taiwan University Hospital and National Taiwan University College of MedicineTaipeiTaiwan
  2. 2.Department of Laboratory Medicine and Internal MedicineNational Taiwan University Hospital and National Taiwan University College of MedicineTaipeiTaiwan

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