Imaging characterization of adnexal lesions: Do CT findings correlate with US?
- 169 Downloads
To compare contrast-enhanced CT and US agreement in characterizing adnexal lesions in late post-menopausal women.
Materials and methods
This was a HIPAA-compliant IRB-approved retrospective review of the contrast-enhanced CTs of 130 late post-menopausal women (> 55 years). The lesions were classified as simple cystic, minimally complex cystic, complex cystic, solid-cystic, or solid based on CT and US morphology. Findings were analyzed to evaluate agreement between CT and US on adnexal lesion characterization.
One forty-one adnexal lesions were assessed by both contrast-enhanced CT and US. Overall, there was good agreement between CT and US, which agreed on the lesion morphology in 114 (81%) cases with an unweighted kappa value of 0.68 (95% CI 0.56–0.78). By CT, 83 (59%) were classified as simple cystic, of which 73/83 (88%) were confirmed as simple cystic by US. Of the remaining 10 CT simple cysts, 9 were reclassified by US as minimally complex cystic and one as complex cystic. Eight of these lesions were benign based on pathology or follow-up imaging, while two lesions remained indeterminate. By CT, 27 lesions (19%) were classified as minimally complex, while US reclassified 13 (48%) of the lesions (eight to simple cystic and five as complex or solid-cystic). Among the 31 remaining lesions, there were 4 (13%) discordances between CT and US.
There is good agreement between CT and US in characterizing adnexal lesion morphology, particularly simple cysts. However, there was significant discordance seen with characterization of minimally complex cysts, indicating that these lesions need US follow-up.
KeywordsAdnexal lesion Ovarian lesion Ovarian cyst CT US
Compliance with ethical standards
Daniel S Hippe wishes to disclose grants from GE Healthcare and Philips Healthcare, outside of the submitted work. The rest of the authors have nothing to disclose.
This article does not contain any studies with human participants or animals performed by any of the authors.
- 2.Greenlee RT, Kessel B, Williams CR, et al. (2010) Prevalence, incidence, and natural history of simple ovarian cysts among women > 55 years old in a large cancer screening trial. Am J Obstet Gynecol 202(373):e1–e9Google Scholar