Ultrasound or MR elastography of liver: which one shall I use?
- 313 Downloads
Liver stiffness is now a well-established noninvasive biomarker for assessing fibrosis in chronic liver disease. MRI-based and ultrasound-based dynamic elastography techniques have been introduced for assessment of liver stiffness and useful in clinical staging of hepatic fibrosis. Several different elastography techniques are now available with each method having inherent strengths and limitations. The published literature generally indicates that MR elastography has a higher diagnostic performance and fewer technical failures than ultrasound-based elastography techniques in assessing hepatic fibrosis. There is also significant potential to further develop elastography techniques to implement multiparametric methods that have promise for distinguishing between processes such as inflammation, fibrosis, venous congestion, and portal hypertension that can result in increased liver stiffness. In this commentary, we compare MR and ultrasound elastography methods and their utility in clinical practice.
KeywordsElastography Ultrasound MRI Shear wave Liver stiffness Hepatic fibrosis
This work has been supported by NIH grant EB017197.
Compliance with ethical standards
Conflict of interest
M.Y. has received research grants from NIH (NIBIB: EB017197). She receives royalties from and holds stock in Resoundant. She has intellectual property rights and a financial interest in MR elastography technology. S.K.V. declares that he has no conflict of interest.
This article does not contain any studies with animals and human participants performed by any of the authors.
- 58.Robert B, Sinkus R, Larrat B, Tanter M, Fink M (2006) A new rheological model based on fractional derivatives for biological tissues. IEEE Ultrasonics Symposium, pp. 1033–1036Google Scholar