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Abdominal Radiology

, Volume 42, Issue 10, pp 2402–2409 | Cite as

CT features of hepatic metastases from hepatoid adenocarcinoma

  • Min-Yung Chang
  • Hye Jin Kim
  • Seung Hyun Park
  • Hyunki Kim
  • Dong Kyu Choi
  • Joon Seok Lim
  • Mi-Suk Park
  • Myeong-Jin Kim
  • Honsoul KimEmail author
Article

Abstract

Purpose

The purpose of this study was to report the imaging presentation of hepatic metastases from hepatoid adenocarcinoma (HAC).

Methods

We retrospectively identified 11 patients (10 men and 1 woman; median age 66) with HAC liver metastasis who underwent contrast-enhanced computed tomography (CT) which included arterial phase and portal venous phase. Two radiologists analyzed the imaging parameters, which included the enhancement pattern on arterial and portal phase images, necrosis, venous thrombi, and overall imaging diagnosis, and arrived at a consensus.

Results

On arterial phase, the liver lesions had global hyper-enhancement (n = 0), heterogeneous hyper-enhancement (63.6%; n = 7/11), peripheral hyper-enhancement (n = 0), iso-enhancement (n = 0/11), or hypo-enhancement (36.4%; n = 4/11). On portal venous phase, homogenous hypo-enhancement (18.2%; n = 2/11) and heterogenous hypo-enhancement (81.8%; n = 9/11) were observed. Venous thromboses occurred in four patients (36.4%; n = 4/11). The overall imaging diagnoses were “HCC-like” in seven patients (63.6%; n = 7/11), “indeterminable” in 1 patient (9.1%; n = 1/11), and “HCC-unlike” in three patients (27.3%; n = 3/11).

Conclusions

The imaging features of HAC liver metastasis were varied. Arterial phase enhancement coupled with venous phase washout (resembling HCC imaging features) was a major finding, but arterial phase hypo-enhancement (distinct from HCC imaging features) was also frequently encountered.

Keywords

Hepatoid adenocarcinoma CT Liver metastasis Hepatocellular carcinoma 

Notes

Compliance with ethical standards

Funding

No funding was received for this study.

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

A waiver of informed consent was obtained from the institutional review board as this was a retrospective study and all patients underwent CT as part of their clinical work-up.

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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  • Min-Yung Chang
    • 1
    • 2
    • 3
  • Hye Jin Kim
    • 1
    • 2
    • 4
  • Seung Hyun Park
    • 1
    • 2
  • Hyunki Kim
    • 5
  • Dong Kyu Choi
    • 6
  • Joon Seok Lim
    • 1
    • 2
  • Mi-Suk Park
    • 1
    • 2
  • Myeong-Jin Kim
    • 1
    • 2
  • Honsoul Kim
    • 1
    • 2
    Email author
  1. 1.Department of RadiologyYonsei University College of MedicineSeoulRepublic of Korea
  2. 2.Research Institute of Radiological ScienceYonsei University College of MedicineSeoulRepublic of Korea
  3. 3.Department of RadiologySeoul National University HospitalSeoulRepublic of Korea
  4. 4.Department of RadiologyAjou University School of MedicineSuwonRepublic of Korea
  5. 5.Department of PathologyYonsei University College of MedicineSeoulRepublic of Korea
  6. 6.New Drug Development CenterDaegu-Gyeongbuk, Medical Innovation Foundation (DGMIF)DaeguRepublic of Korea

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