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Abdominal Radiology

, Volume 42, Issue 5, pp 1472–1484 | Cite as

Neuroendocrine neoplasms of the genitourinary tract in adults: cross-sectional imaging spectrum

  • Venkata S. Katabathina
  • Raghu Vikram
  • Adeniran Olaoya
  • Raj Mohan Paspulati
  • Marlo M. Nicolas
  • Priya Rao
  • Atif Zaheer
  • Srinivasa R. Prasad
Pictorial Essay
  • 329 Downloads

Abstract

Neuroendocrine (NE) neoplasms of the genitourinary (GU) tract in adults are rare tumors with distinct histopathology and variable biological behavior and imaging findings. They may be primary or metastatic in origin. The spectrum of primary GU tract NE neoplasms includes carcinoid, small cell carcinoma, large cell NE carcinoma, and paraganglioma. The tumors commonly show positivity to specific immunohistochemical markers and characteristic dense-core granules at the ultra-structural level. Although imaging findings are nonspecific and accurate differentiation from the more common malignancies of the individual organs is not possible, cross-sectional imaging modalities play an important role in the diagnosis, staging, and surveillance of these tumors. Somatostatin receptor scintigraphy (octreotide scan) may be useful in the detection and treatment of metastatic disease in select patients. Knowledge of the various NE tumors of the adult GU tract and familiarity with their pathological and imaging findings permit optimal patient management.

Keywords

Neuroendocrine Tumors Genitourinary Imaging 

Notes

Compliance with ethical standards

Funding

No funding was received for this study.

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

Informed consent

Statement of informed consent was not applicable since the manuscript does not contain any patient data.

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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Venkata S. Katabathina
    • 1
  • Raghu Vikram
    • 2
  • Adeniran Olaoya
    • 5
  • Raj Mohan Paspulati
    • 3
  • Marlo M. Nicolas
    • 6
  • Priya Rao
    • 7
  • Atif Zaheer
    • 4
  • Srinivasa R. Prasad
    • 2
  1. 1.Department of RadiologyUniversity of Texas Health Science Center at San AntonioSan AntonioUSA
  2. 2.Department of RadiologyUniversity of Texas MD Anderson Cancer CenterHoustonUSA
  3. 3.Department of RadiologyCase Western Reserve UniversityClevelandUSA
  4. 4.Department of RadiologyJohns Hopkins UniversityBaltimoreUSA
  5. 5.University of Texas School of Public HealthHoustonUSA
  6. 6.Department of PathologyUniversity of Texas Health Science Center at San AntonioSan AntonioUSA
  7. 7.Department of PathologyUniversity of Texas MD Anderson Cancer CenterHoustonUSA

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