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Abdominal Imaging

, Volume 40, Issue 7, pp 2660–2666 | Cite as

Comparison of PET with PET/CT in detecting peritoneal carcinomatosis: a meta-analysis

  • Jinkui Li
  • Ruifeng Yan
  • Junqiang LeiEmail author
  • Changqin Jiang
Review Article

Abstract

Purpose

The study aims to perform a meta-analysis to compare the diagnostic value of FDG PET with PET/CT in detecting peritoneal carcinomatosis (PC) to identify the potentially most useful diagnostic modality.

Methods

A computer-aided search was performed in the Cochrane Library, PubMed, EMBASE, Web of Science, the China Biological Medicine Database, VIP, China National Knowledge Infrastructure database, and Wanfang databases for articles concerning diagnosis of peritoneal metastases with PET or PET/CT. QUADAS was used to evaluate the included articles’ quality.

Results

On a per-patient basis, the pooled sensitivity of PET/CT (84%) was significantly higher than that of PET (60%), and the pooled specificity of PET (98%) was markedly higher than that for PET/CT (94%). On a per-lesion basis, the pooled sensitivity and specificity of PET/CT were 87 and 95%, respectively. Only 1 PET study on a per-lesion basis, its sensitivity is 65.8 and specificity is 94.1%.

Conclusions

PET and PET/CT are powerful imaging techniques for detection and characterization of PC. PET/CT can be used as a screening tool and it may be acceptable to use PET as a diagnosis tool.

Keywords

PET Positron emission tomography PET/CT Peritoneal carcinomatosis Meta-analysis 

Notes

Disclosure

The scientific guarantor of this publication is Junqiang Lei. The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article. The authors state that this work has not received any funding. No complex statistical methods were necessary for this paper. Institutional Review Board approval was obtained. Only if the study is on human subjects: Written informed consent was not required for this study because the study is a secondary research evidence. Some study subjects or cohorts have been previously reported in XXX. Methodology: diagnostic study.

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Jinkui Li
    • 1
  • Ruifeng Yan
    • 1
  • Junqiang Lei
    • 2
    Email author
  • Changqin Jiang
    • 1
  1. 1.The First Clinical Medical School of Lanzhou UniversityLanzhouChina
  2. 2.The First Hospital of Lanzhou UnivesityLanzhouChina

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