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Abdominal Imaging

, Volume 40, Issue 5, pp 965–974 | Cite as

CT and MR enterography in Crohn’s disease: current and future applications

  • David H. BruiningEmail author
  • Gauraang Bhatnagar
  • Jordi Rimola
  • Stuart Taylor
  • Ellen M. Zimmermann
  • Joel G. Fletcher
Article

Over the last two decades, radiologic imaging has become a vital component in the assessment of patients with known or suspected Crohn’s disease (CD). Increased utilization of cross-sectional imaging techniques has been driven by both disease- and patient-specific factors, as well as the realization that other clinical, laboratory, and even surgical evaluations may miss CD-related inflammation, penetrating complications, and obstructive disease. As a disease process, the protean symptoms of CD are often non-specific such as abdominal pain and diarrhea [1]. Even validated clinical indices of CD severity, such as the Crohn’s Disease Index of Activity (CDAI), the clinical endpoint for most therapeutic trials in CD, show poor correlation with biologic activity, especially in certain populations such as patients with fistulizing or obstructing disease [2, 3, 4]. In addition, there is little clinical suspicion of Crohn’s fistulae and strictures in a substantial proportion of patients with...

Keywords

Crohn’s disease CT enterography MR enterography 

Abbreviations

CD

Crohn’s disease

CT

Computed tomography

CTE

CT enterography

IBD

Inflammatory bowel disease

MR

Magnetic resonance

MRE

MR enterography

Notes

Conflict of interest

JR: Robarts Clinical Trials (Consulting), AbbVie (Consulting), Bristol Myers Squibb (Consulting), Genentech (Research Support); ST: Robarts Clinical Trials (Consulting); and DHB, GB, EMZ, and JG declare that they have no conflict of interest.

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • David H. Bruining
    • 1
    Email author
  • Gauraang Bhatnagar
    • 2
  • Jordi Rimola
    • 3
  • Stuart Taylor
    • 2
  • Ellen M. Zimmermann
    • 4
  • Joel G. Fletcher
    • 5
  1. 1.Division of Gastroenterology and HepatologyMayo ClinicRochesterUSA
  2. 2.Centre for Medical ImagingUniversity CollegeLondonUK
  3. 3.Department of Radiology, Hospital Clinic BarcelonaUniversity of BarcelonaBarcelonaSpain
  4. 4.Division of Gastroenterology, Hepatology, and NutritionUniversity of Florida College of MedicineGainesvilleUSA
  5. 5.Department of RadiologyMayo ClinicRochesterUSA

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