Abdominal Imaging

, Volume 40, Issue 1, pp 56–63 | Cite as

Alveolar echinococcosis: correlation between hepatic MRI findings and FDG-PET/CT metabolic activity

  • Amel Azizi
  • Oleg Blagosklonov
  • Ahmed Lounis
  • Louis Berthet
  • Dominique-Angèle Vuitton
  • Solange Bresson-Hadni
  • Eric DelabrousseEmail author



To correlate the appearance of alveolar echinococcosis (AE) hepatic lesions in magnetic resonance imaging (MRI) as defined by Kodama, to the metabolic activity visualized in 18-fluoro-deoxyglucose positron emission tomography combined with computed tomography (PET/CT).

Materials and methods

Forty-two patients diagnosed with AE and who underwent both MRI and PET/CT were included. The forty-two hepatic lesions were divided into five types according to Kodama’s classification by three independent readers blinded with regard to the PET/CT information. Concerning PET/CT, two independent readers, unaware of the MRI information, considered the results as positive when an increased FDG-uptake was observed at 1 or 3 h after FDG-injection, and as negative when no increased uptake was noted. Inter-observer agreement was assessed by using κ statistics.


Forty-two lesions were counted and the mean diameter of overall evaluated lesions was 6.3 cm. One lesion (2.4%) was categorized as type 1, 11 (26.2%) as type 2, 24 (57.1%) as type 3, 3 (7.1%) as type 4, and 3 (7.1%) as type 5. The inter-observer analysis found a κ coefficient of 0.96. All type-1, 90.9% of type-2 and 87.5% of type-3 lesions showed an increased FDG-uptake on PET/CT images. All non-microcystic AE liver lesions (types 4 and 5) showed no abnormal increased FDG-uptake on PET/CT images. The inter-observer analysis at 1 and 3 h found a κ coefficient of 0.95 and 0.92, respectively.


In patients with AE liver lesions, the absence of microcysts on MRI is strongly correlated to a metabolically inactive disease.


Alveolar echinococcosis Liver MRI FDG-PET/CT Metabolic activity 


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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Amel Azizi
    • 1
  • Oleg Blagosklonov
    • 2
    • 3
  • Ahmed Lounis
    • 1
  • Louis Berthet
    • 2
  • Dominique-Angèle Vuitton
    • 4
  • Solange Bresson-Hadni
    • 4
  • Eric Delabrousse
    • 1
    • 3
    Email author
  1. 1.Department of RadiologyUniversity HospitalBesançonFrance
  2. 2.Departmentof Nuclear MedicineUniversity HospitalBesançonFrance
  3. 3.EA 4662 Nanomedicine Lab, Imagery and TherapeuticsUniversity of Franche-ComtéBesançonFrance
  4. 4.WHO Collaborating Centre for Prevention and Treatment of Human EchinococcosisBesançonFrance

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