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Abdominal Imaging

, Volume 38, Issue 1, pp 144–153 | Cite as

Metastatic disease to the pancreas: pathologic spectrum and CT patterns

  • Sameer Ahmed
  • Pamela T. JohnsonEmail author
  • Ralph Hruban
  • Elliot K. Fishman
Article

Abstract

Metastases to the pancreas are rare; nevertheless, early detection allows for appropriate treatment and improved outcomes for metastatic disease. Computed tomography plays a pivotal role in characterizing these tumors, as demonstrated in this pictorial review. Given significant differences in prognosis and treatment, it is crucial to differentiate primary and secondary pancreatic lesions; however, this may not be possible based on imaging features alone.

Keywords

Pancreas CT Renal cell carcinoma Metastatic disease 

References

  1. 1.
    Tsitouridis I, Diamantopoulou A, Michaelides M, Arvanity M, Papaioannou S (2010) Pancreatic metastases: CT and MRI findings. Diagn Interv Radiol 16(1):45–51. doi: 10.4261/1305-3825.DIR.1996-08.1 PubMedGoogle Scholar
  2. 2.
    Sweeney AD, Fisher WE, Wu MF, Hilsenbeck SG, Brunicardi FC (2010) Value of pancreatic resection for cancer metastatic to the pancreas. J Surg Res 160(2):268–276PubMedCrossRefGoogle Scholar
  3. 3.
    Klein KA, Stephens DH, Welch TJ (1998) CT characteristics of metastatic disease of the pancreas. Radiographics 18(2):369–378PubMedGoogle Scholar
  4. 4.
    Scatarige JC, Horton KM, Sheth S, Fishman EK (2001) Pancreatic parenchymal metastases: observations on helical CT. AJR Am J Roentgenol 176(3):695–699PubMedGoogle Scholar
  5. 5.
    Roland CF, van Heerden JA (1989) Nonpancreatic primary tumors with metastasis to the pancreas. Surg Gynecol Obstet 168(4):345–347PubMedGoogle Scholar
  6. 6.
    Mecho S, Quiroga S, Cuellar H, Sebastia C (2009) Pancreatic metastasis of renal cell carcinoma: multidetector CT findings. Abdom Imaging 34(3):385–389. doi: 10.1007/s00261-008-9391-9 PubMedCrossRefGoogle Scholar
  7. 7.
    Ferrozzi F, Bova D, Campodonico F, et al. (1997) Pancreatic metastases: CT assessment. Eur Radiol 7(2):241–245PubMedCrossRefGoogle Scholar
  8. 8.
    Boudghene FP, Deslandes PM, LeBlanche AF, Bigot JM (1994) US and CT imaging features of intrapancreatic metastases. J Comput Assist Tomogr 18(6):905–910PubMedCrossRefGoogle Scholar
  9. 9.
    DeWitt J, Jowell P, Leblanc J, et al. (2005) EUS-guided FNA of pancreatic metastases: a multicenter experience. Gastrointest Endosc 61(6):689–696PubMedCrossRefGoogle Scholar
  10. 10.
    Ascenti G, Visalli C, Genitori A, et al. (2004) Multiple hypervascular pancreatic metastases from renal cell carcinoma: dynamic MR and spiral CT in three cases. Clin Imaging 28(5):349–352. doi: 10.1016/S0899-7071(03)00198-0 PubMedCrossRefGoogle Scholar
  11. 11.
    Kelekis NL, Semelka RC, Siegelman ES (1996) MRI of pancreatic metastases from renal cancer. J Comput Assist Tomogr 20(2):249–253PubMedCrossRefGoogle Scholar
  12. 12.
    Sato M, Okumura T, Kaito K, et al. (2009) Usefulness of FDG-PET/CT in the detection of pancreatic metastases from lung cancer. Ann Nucl Med 23(1):49–57. doi: 10.1007/s12149-008-0205-5 PubMedCrossRefGoogle Scholar
  13. 13.
    Ng CS, Loyer EM, Iyer RB, et al. (1999) Metastases to the pancreas from renal cell carcinoma: findings on three-phase contrast-enhanced helical CT. AJR Am J Roentgenol 172(6):1555–1559PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Sameer Ahmed
    • 1
  • Pamela T. Johnson
    • 2
    Email author
  • Ralph Hruban
    • 3
  • Elliot K. Fishman
    • 2
  1. 1.School of MedicineJohns Hopkins UniversityBaltimoreUSA
  2. 2.Department of RadiologyJohns Hopkins HospitalBaltimoreUSA
  3. 3.Department of PathologyJohns Hopkins HospitalBaltimoreUSA

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