Abdominal Imaging

, 34:634

Extrapancreatic neural plexus invasion by pancreatic carcinoma: characteristics on magnetic resonance imaging

  • Xiao Ming Zhang
  • Donald G. Mitchell
  • Agnes Witkiewicz
  • Sachit Verma
  • Diane Bergin
Article

DOI: 10.1007/s00261-008-9440-4

Cite this article as:
Zhang, X.M., Mitchell, D.G., Witkiewicz, A. et al. Abdom Imaging (2009) 34: 634. doi:10.1007/s00261-008-9440-4

Abstract

Background: Our objective is to study the characteristics of extrapancreatic neural plexus invasion by pancreatic carcinoma on MR imaging. Methods: 20 patients with both pancreatic carcinoma and extrapancreatic neural plexus invasion confirmed by pathology were recruited in this study. MR imaging was performed within 1 month before surgery. On MR images, signal intensity at the site of potential extrapancreatic neural plexus invasion, lymph nodes and tumor size were noted. The relationship of extrapancreatic neural plexus invasion to these findings was analyzed. Results: Signs of extrapancreatic neural plexus invasion were depicted on MR imaging in 80% of patients, which included streaky and strand-like signal intensity structure in fat tissue in 50% of patients and irregular masses adjacent to tumor in 30%. Signal intensity at invasion site was similar to that of pancreatic carcinoma. The frequencies of patients with vascular invasion and with lymph nodes larger than 5 mm were, respectively, 50% and 55%. Tumor diameter was 24 ± 7 mm on MR imaging. Extrapancreatic neural plexus invasion was correlated with vascular invasion (r = 0.58, P < 0.005), slightly related with lymphadenopathy (r = 0.35, 0.1 > P > 0.05), but not related with tumor size. Conclusion: MR imaging is useful to depict extrapancreatic neural plexus invasion by pancreatic carcinoma.

Keywords

Pancreas Carcinoma Extrapancreatic neural plexus Magnetic resonance Invasion 

Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Xiao Ming Zhang
    • 1
  • Donald G. Mitchell
    • 2
  • Agnes Witkiewicz
    • 3
  • Sachit Verma
    • 2
  • Diane Bergin
    • 2
  1. 1.Department of RadiologyAffiliated Hospital of North Sichuan Medical CollegeNanchongPeople’s Republic of China
  2. 2.Department of RadiologyThomas Jefferson University HospitalPhiladelphiaUSA
  3. 3.Department of PathologyThomas Jefferson University HospitalPhiladelphiaUSA

Personalised recommendations