Localized Castleman disease in retroperitoneum: newly discovered features by multi-detector helical CT
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We describe CT features of our three cases with localized Castleman disease in the retroperitoneum and review literature. Besides those CT features, which have been reported before, we mainly present some newly discovered CT findings of the disease. These new CT findings include the sign of peripheral ‘rim-like’ enhancement at the early phase of an enhanced CT scan, a higher ratio of the left sided retroperitoneal location to the right side and the presence of local peritoneal thickening around the lesion. In addition, the feeding artery of the lesion is more visually pronounced than ever before by a 16-detector CT scanner.
After reviewing the literature and comparing with their histological findings, we suggest these newly discovered findings are relatively characteristic CT features of the disease. Moreover, multi-detector helical CT can now show more details of the disease than ever before.
KeywordsCastleman disease Angiofollicular lymph node hyperplasia Giant lymph node hyperplasia Multi-detector Computed Tomography Retroperitoneum
Micheal Zhou PhD, Alex Chao MD, for their assistance in checking and reviewing this paper while I’m studying and training in the Image Processing and Informatics Laboratory, University of Southern California, USA.
- 2.Toni LM, John KMCT (2000) Features of Castleman disease of the abdomen and pelvis. AJR 175:115–118Google Scholar
- 3.Jung KT, Koo HJ, Hoon KY et al (2001) Castleman disease of the abdomen: imaging spectrum and clinicopathologic correlations. JCAT 25:207–214Google Scholar
- 4.Wang R, Wang Y, Tan G et al (2002) Localized Castleman’s disease of the abdomen: CT and histo-pathologic correlation. J Chin Radiol 36:159–162Google Scholar
- 6.Ota T, Mitsuyoshi A, Zaima A et al (1997) Visualization of central stellate fibrosis in hyaline vascular type Castleman disease. Br J Rad. 70:1060–1062Google Scholar
- 12.Lewis WH (2000) The lymphatics of the abdomen and pelvis. In: Gray’s anatomy of the human body, 20th edn, New York. [E-book] Bartleby.comGoogle Scholar