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Abdominal Imaging

, Volume 31, Issue 4, pp 387–399 | Cite as

Gastrointestinal stromal tumors

  • A. DarnellEmail author
  • E. Dalmau
  • C. Pericay
  • E. Musulén
  • J. Martín
  • J. Puig
  • A. Malet
  • E. Saigí
  • M. Rey
UPDATE

Abstract

Background

We reviewed radiologic features of gastrointestinal stromal tumors (GISTs) and correlated them with clinical and pathologic findings.

Methods

We investigated a series of 39 c-Kit–positive GISTs. Clinical and radiologic findings and management of these patients were recorded.

Results

Twenty women and 19 men (mean age 64 years) had histologically proved GIST. Tumor locations were the small bowel (n = 20), stomach (n = 14), rectum (n = 4), and omentum (n = l). Symptoms at presentation were most frequently gastrointestinal bleeding (n = 14) and abdominal pain (n = l1). Tumors were classified as very low risk (n = 2), low risk (n = 10), intermediate risk (n = 12), and high risk (n = 11). Ultrasonography, computed tomography, magnetic resonance, digital subtraction angiography, and barium series were used in the evaluation of these tumors. Most tumors were seen as well-delineated soft tissue masses with heterogeneous contrast enhancement. Necrosis, calcification, and ulceration were most commonly seen in large tumors that presented a more aggressive behavior.

Conclusion

GISTs can arise anywhere in the gastrointestinal tract and present a great variety of clinical and radiologic features, depending mostly on size and location.

Keywords

Gastrointestinal stromal tumor Gastrointestinal tract, neoplasm Gastrointestinal tract, magnetic resonance 

Notes

Acknowledgments

We thank John Giba for linguistic support in the preparation of this report.

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Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • A. Darnell
    • 1
    Email author
  • E. Dalmau
    • 2
  • C. Pericay
    • 2
  • E. Musulén
    • 3
  • J. Martín
    • 1
  • J. Puig
    • 1
  • A. Malet
    • 1
  • E. Saigí
    • 2
  • M. Rey
    • 3
  1. 1.Department of RadiologyUDIAT-CD, Corporació Sanitària Parc TaulíParc Taulí s/n 08208 SabadellSpain
  2. 2.Department of OncologyCorporació Sanitària Parc TaulíParc Taulí s/n 08208 SabadellSpain
  3. 3.Department of PathologyUDIAT-CD, Corporació Sanitària Parc TaulíParc Taulí s/n 08208 SabadellSpain

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