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Abdominal Imaging

, Volume 28, Issue 1, pp 0087–0091 | Cite as

Impaired gallbladder function in spinal cord injury on quantitative Tc-99m DISIDA cholescintigraphy

  • Y.-C. Fong
  • H. C. Hsu
  • S.-S. Sun
  • A. Kao
  • C.-C. Lin
  • C.-C. Lee

Abstract

Background: Patients with spinal cord injury (SCI) have increased prevalences of gallstones and acute acalculous cholecystitis. A possible explanation for the increased prevalence of gallstone disease in SCI patients is decreased gallbladder motility causing gallbladder stasis, a known risk factor for gallstone disease. We investigated gallbladder function in SCI.

Methods: Twenty-five normal control subjects and 50 SCI patients were included in this study. Gallbladder function was measured by technium 99m–labeled imino-diacetic acid analogue (Tc-99m DISIDA) cholescintigraphy and represented by the filling fraction (FF) and the ejection fraction (EF). The SCI patients were assigned to subgroups: old versus young, female versus male, high- versus low-level injury, and long versus short injury duration.

Results: Forty-two percent of SCI patients had abnormal FFs and 54% of SCI patients had abnormal EFs. Significantly decreased FF and EF values were found in SCI patients, especially in those who were female and had high-level injuries.

Conclusion: With the use of quantitative Tc-99m DISIDA cholescintigraphy, we found that SCI can significantly impair gallbladder function.

Key words: Gallbladder function—Spinal cord injury—Technium 99m–labeled imino-diacetic acid analogue cholescintigraphy. 

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Copyright information

© Springer-Verlag New York Inc. 2003

Authors and Affiliations

  • Y.-C. Fong
    • 1
  • H. C. Hsu
    • 1
  • S.-S. Sun
    • 2
  • A. Kao
    • 2
  • C.-C. Lin
    • 4
  • C.-C. Lee
    • 3
  1. 1.Department of Orthopedics, China Medical College Hospital, No. 2 Yuh-Der Road, Taichung 404, TaiwanTW
  2. 2.Department of Nuclear Medicine, China Medical College Hospital, No. 2 Yuh-Der Road, Taichung 404, TaiwanTW
  3. 3.Department of Medical Research, China Medical College Hospital, No. 2 Yuh-Der Road, Taichung 404, TaiwanTW
  4. 4.Department of Family Medicine, China Medical College Hospital, No. 2 Yuh-Der Road, Taichung 404, TaiwanTW

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