Comment on: “the FDG PET/CT score” for the diagnosis of malignant pleural effusion

  • Dharmender MalikEmail author
Letter to the Editor
Part of the following topical collections:
  1. Oncology – Chest

Dear Sir,

Pleural effusion, caused by a number of malignant and benign diseases, is a common and challenging medical problem. Malignant pleural effusion (MPE) is frequently observed in multiple malignancies, with lung cancer being the most frequent underlying malignancy [1, 2]. The diagnosis of malignant pleural effusion adversely affects a patient’s staging and prognosis and may alter the therapeutic approach [3]. Computed tomography (CT) and positron emission tomography (PET) as non-invasive methods have been used to characterize pleural effusion as malignant or benign and can trigger the determination of etiology in some cases [4]. Meta-analysis by Porcel et al. had predicted the pooled sensitivity, specificity, and positive likelihood ratio of 81%, 74%, and 3.22 respectively with area under the curve of 0.838 for identifying malignant effusion using semiquantitative interpretation of integrated PET-CT imaging system [5]. However, none of the imaging measurements appear to predict...


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No conflict of interest to declare.

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This article does not contain any studies with human participants or animals performed by any of the authors.


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© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Nuclear Medicine and PET/CT, Centre for Advanced Research in imaging, Neuroscience and Genomics (CARING)Sir Ganga Ram HospitalNew DelhiIndia

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