Comment on: “the FDG PET/CT score” for the diagnosis of malignant pleural effusion
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Pleural effusion, caused by a number of malignant and benign diseases, is a common and challenging medical problem. Malignant pleural effusion (MPE) is frequently observed in multiple malignancies, with lung cancer being the most frequent underlying malignancy [1, 2]. The diagnosis of malignant pleural effusion adversely affects a patient’s staging and prognosis and may alter the therapeutic approach . Computed tomography (CT) and positron emission tomography (PET) as non-invasive methods have been used to characterize pleural effusion as malignant or benign and can trigger the determination of etiology in some cases . Meta-analysis by Porcel et al. had predicted the pooled sensitivity, specificity, and positive likelihood ratio of 81%, 74%, and 3.22 respectively with area under the curve of 0.838 for identifying malignant effusion using semiquantitative interpretation of integrated PET-CT imaging system . However, none of the imaging measurements appear to predict...
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- 4.Sun Y, Yu H, Ma J, Lu P. The role of 18F-FDG PET/CT integrated imaging in distinguishing malignant from benign pleural effusion. PLoS One. 2016;11(8):e0161764. https://doi.org/10.1371/journal.pone.0161764.eCollection2016.CrossRefPubMedPubMedCentralGoogle Scholar