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PET/MRI with a 68Ga-PSMA ligand for the detection of prostate cancer

  • Ali Afshar-OromiehEmail author
  • Uwe Haberkorn
  • Boris Hadaschik
  • Gregor Habl
  • Matthias Eder
  • Michael Eisenhut
  • Heinz-Peter Schlemmer
  • Matthias C. Roethke
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Keywords

Prostate Cancer Apparent Diffusion Coefficient Additional Radiation Exposure Superior Soft Tissue Contrast PSMA Ligand 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Conflicts of interest

None.

References

  1. 1.
    Eder M, Schäfer M, Bauder-Wüst U, Hull WE, Wangler C, Mier W, et al. 68Ga-complex lipophilicity and the targeting property of a urea-based PSMA inhibitor for PET imaging. Bioconjug Chem. 2012;23:688–97.PubMedCrossRefGoogle Scholar
  2. 2.
    Afshar-Oromieh A, Haberkorn U, Eder M, Eisenhut M, Zechmann C. [68Ga]Gallium-labelled PSMA ligand as superior PET tracer for the diagnosis of prostate cancer: comparison with 18F-FECH. Eur J Nucl Med Mol Imaging. 2012;39(6):1085–6.PubMedCrossRefGoogle Scholar
  3. 3.
    Afshar-Oromieh A, Malcher A, Eder M, Eisenhut M, Linhart HG, Hadaschik BA, et al. PET imaging with a [68Ga]Gallium-labelled PSMA ligand for the diagnosis of prostate cancer: biodistribution in humans and first evaluation of tumour lesions. Eur J Nucl Med Mol Imaging. 2013;40(4):486–95.PubMedCrossRefGoogle Scholar
  4. 4.
    Barrett JA, Coleman RE, Goldsmith SJ, Vallabhajosula S, Petry NA, Cho S, et al. First-in-man evaluation of 2 high-affinity PSMA-avid small molecules for imaging prostate cancer. J Nucl Med 2013;54(3):380–7.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Ali Afshar-Oromieh
    • 1
    Email author
  • Uwe Haberkorn
    • 1
    • 2
  • Boris Hadaschik
    • 3
  • Gregor Habl
    • 4
  • Matthias Eder
    • 5
  • Michael Eisenhut
    • 5
  • Heinz-Peter Schlemmer
    • 6
  • Matthias C. Roethke
    • 6
  1. 1.Department of Nuclear MedicineUniversity Hospital HeidelbergHeidelbergGermany
  2. 2.Clinical Cooperation Unit Nuclear MedicineGerman Cancer Research CenterHeidelbergGermany
  3. 3.Department of UrologyUniversity Hospital HeidelbergHeidelbergGermany
  4. 4.Department of Radiation Oncology and TherapyUniversity Hospital HeidelbergHeidelbergGermany
  5. 5.Department of Radiopharmaceutical ChemistryGerman Cancer Research CenterHeidelbergGermany
  6. 6.Department of RadiologyGerman Cancer Research Center (DKFZ)HeidelbergGermany

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