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[68Ga]Gallium-labelled PSMA ligand as superior PET tracer for the diagnosis of prostate cancer: comparison with 18F-FECH

  • A. Afshar-Oromieh
  • U. Haberkorn
  • M. Eder
  • M. Eisenhut
  • CM. ZechmannEmail author
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Keywords

Prostate Cancer Positron Emission Tomography Androgen Ligand Binding Urinary Bladder 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

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    Ghosh A, Heston WD. Tumor target prostate specific membrane antigen (PSMA) and its regulation in prostate cancer. J Cell Biochem 2004;91:528–39.PubMedCrossRefGoogle Scholar
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    Chang SS, O’Keefe DS, Bacich DJ, Reuter VE, Heston WD, Gaudin PB. Prostate-specific membrane antigen is produced in tumor-associated neovasculature. Clin Cancer Res 1999;5:2674–81.PubMedGoogle Scholar
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    Chang SS, Reuter VE, Heston WD, Bander NH, Grauer LS, Gaudin PB. Five different anti-prostate-specific membrane antigen (PSMA) antibodies confirm PSMA expression in tumor-associated neovasculature. Cancer Res 1999;59:3192–8.PubMedGoogle Scholar
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    Hillier SM, Maresca KP, Femia FJ, Marquis JC, Foss CA, Nguyen N, Zimmerman CN, Barrett JA, Eckelman WC, Pomper MG, Joyal JL, Babich JW. Preclinical evaluation of novel glutamate-urea-lysine analogues that target prostate-specific membrane antigen as molecular imaging pharmaceuticals for prostate cancer. Cancer Res 2009;69(17):6932–40.PubMedCrossRefGoogle Scholar
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    Eder M, Schäfer M, Bauder-Wüst U, Wängler C, Mier W, Haberkorn U, Eisenhut M. The 68Ga-complex lipophilicity and the targeting property of a urea based PSMA inhibitor for PET imaging. Bioconjug Chem 2011, in revision.Google Scholar

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • A. Afshar-Oromieh
    • 1
  • U. Haberkorn
    • 1
  • M. Eder
    • 2
  • M. Eisenhut
    • 2
  • CM. Zechmann
    • 1
    Email author
  1. 1.Department of Nuclear MedicineUniversity Hospital HeidelbergHeidelbergGermany
  2. 2.Department of Radiopharmaceutical ChemistryGerman Cancer Research CenterHeidelbergGermany

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