EANM procedure guideline for brain perfusion SPECT using 99mTc-labelled radiopharmaceuticals, version 2

  • Özlem L. Kapucu
  • Flavio Nobili
  • Andrea Varrone
  • Jan Booij
  • Thierry Vander Borght
  • Kjell Någren
  • Jacques Darcourt
  • Klaus Tatsch
  • Koen J. Van Laere


These guidelines summarize the current views of the European Association of Nuclear Medicine Neuroimaging Committee (ENC). The purpose of the guidelines is to assist nuclear medicine practitioners when making recommendations, performing, interpreting, and reporting the results of brain perfusion single photon emission computed tomography (SPECT) studies using 99mTc-labelled radiopharmaceuticals. The aim is to achieve a high quality standard for brain perfusion SPECT imaging, which will increase the diagnostic impact of this technique in clinical practice. The present document replaces a former version of the guideline published in 2001 which was inspired by the Society of Nuclear Medicine Procedure Guideline for Brain Perfusion SPECT [1], the views of the Society of Nuclear Medicine Brain Imaging Council [2], and the individual experience of experts in European countries. The guidelines are intended to present information specifically adapted to European practice. The information provided should be taken in the context of local conditions and regulations.


Brain Perfusion SPECT HMPAO ECD Epilepsy Dementia 


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Copyright information

© EANM 2009

Authors and Affiliations

  • Özlem L. Kapucu
    • 1
  • Flavio Nobili
    • 2
  • Andrea Varrone
    • 3
  • Jan Booij
    • 4
  • Thierry Vander Borght
    • 5
  • Kjell Någren
    • 6
  • Jacques Darcourt
    • 7
  • Klaus Tatsch
    • 8
  • Koen J. Van Laere
    • 9
  1. 1.Department of Nuclear Medicine, Faculty of MedicineGazi UniversityAnkaraTurkey
  2. 2.Clinical Neurophysiology Unit, San Martino HospitalUniversity of GenoaGenoaItaly
  3. 3.Department of Clinical Neuroscience, Psychiatry SectionKarolinska InstitutetStockholmSweden
  4. 4.Department of Nuclear Medicine, Academic Medical CenterUniversity of AmsterdamAmsterdamThe Netherlands
  5. 5.Nuclear Medicine DivisionUniversité Catholique de Louvain, Mont-Godinne Medical CenterLouvain-la-NeuveBelgium
  6. 6.Department of Clinical Physiology and Nuclear Medicine, RigshospitaletUniversity of CopenhagenCopenhagenDenmark
  7. 7.Nuclear Medicine, Centre Antoine Lacassagne and University HospitalUniversité de Nice Sophia AntipolisNiceFrance
  8. 8.Department of Nuclear Medicine, Municipal Hospital of Karlsruhe Inc.KarlsruheGermany
  9. 9.Division of Nuclear MedicineUniversity Hospital LeuvenLeuvenBelgium

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