Multislice CT coronary angiography: how to do it and what is the current clinical performance?

  • Filippo Cademartiri
  • Joanne D. Schuijf
  • Nico R. Mollet
  • Patrizia Malagutti
  • Giuseppe Runza
  • Jeroen J. BaxEmail author
  • Pim J. de Feyter
Occasional Survey


The introduction of multislice computed tomography (MSCT) has allowed non-invasive coronary angiography. Although widely applied, extensive information on technical details of the technique is lacking. This survey offers detailed information on patient preparation, data acquisition, reconstruction and interpretation. In addition, a summary of the available studies using MSCT for non-invasive angiography is provided. Based on pooled analysis of direct comparisons between MSCT and invasive angiography, the weighted mean sensitivity and specificity of current 16-slice MSCT for the detection of coronary artery disease are 88% and 96%, respectively. At present, the technique is particularly well suited for reliable exclusion of coronary artery disease. It is important to emphasise that MSCT only provides anatomical images, visualising the presence of atherosclerosis; information on the haemodynamic significance of these lesions (i.e. ischaemia) cannot be derived.


Multislice computed tomography Coronary artery disease Image reconstruction 



J.D. Schuijf is financially supported by The Netherlands Heart Foundation, The Hague, The Netherlands, grant number 2002B105.


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Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  • Filippo Cademartiri
    • 1
    • 2
    • 3
  • Joanne D. Schuijf
    • 4
    • 5
    • 6
  • Nico R. Mollet
    • 1
    • 2
  • Patrizia Malagutti
    • 1
  • Giuseppe Runza
    • 1
    • 2
    • 3
  • Jeroen J. Bax
    • 4
    Email author
  • Pim J. de Feyter
    • 1
    • 2
  1. 1.Department of RadiologyErasmus Medical CenterRotterdamThe Netherlands
  2. 2.Department of CardiologyErasmus Medical CenterRotterdamThe Netherlands
  3. 3.Department of RadiologyAzienda Ospedaliera di ParmaParmaItaly
  4. 4.Dept of CardiologyLeiden University Medical CenterLeidenThe Netherlands
  5. 5.Department of RadiologyLeiden University Medical CenterLeidenThe Netherlands
  6. 6.The Interuniversity Cardiology Institute of the NetherlandsUtrechtThe Netherlands

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