[Tc(CO)3]+ chemistry: a promising new concept for SPECT?



  1. 1.
    Top S, El Hafa H, Vessiees A, et al. Rhenium carbonyl complexes of β-estradiol derivatives with high affinity for the estradiol receptor: an approach to selective organometallic radiopharmaceuticals. J Am Chem Soc 1995; 117:8372–8380.Google Scholar
  2. 2.
    Top S, Vessieres A, Jaouen G. Synthetic strategy for organometallic complexes of rhenium with exceptionally high affinity for the oestradiol receptor; their potential use as imaging and therapeutic agents. J Chem Soc Chem Commun 1994; 453–454.Google Scholar
  3. 3.
    Spradau TW, Edwards WB, Anderson CJ, Welch MJ, Katzenellenbogen JA. Synthesis and biological evaluation of Tc-99m-cyclopentadienyltricarbonytechnetium-labeled octreotide. Nucl Med Biol 1999; 26:1–7.CrossRefPubMedGoogle Scholar
  4. 4.
    Nicolini M, Mazzi U. Technetium, rhenium and other metals in chemistry and nuclear medicine 6. Padova: SGEditoriali, 2002.Google Scholar
  5. 5.
    Alberto R, Ortner K, Wheatley N, Schibli R, Schubiger AP. Synthesis and properties of boranocarbonate: a convenient in situ CO source for the aqueous preparation of [99mTc(OH2)3(CO)3]+. J Am Chem Soc 2001; 123:3135–3136.PubMedGoogle Scholar
  6. 6.
    Albergo R, Schibli R, Egli A. Method for the preparation of facial metal tricarbonyl compounds and their use in the labeling of biologically active substrates. U.S. Patent 6 344 178. February 2002.Google Scholar
  7. 7.
    Uetake M, Koizumi K, Yagawa A, Nogata H, Tezuka T, Kono H, Ozawa T, Kusano T, Miyabukuro M, Hosaka M. Use of Tc-99m DTPA galactosyl human serum albumin to predict postoperative residual liver function. Clin Nucl Med 1999; 24:428–434.CrossRefPubMedGoogle Scholar
  8. 8.
    Hwang EH, Taki J, Shuke N, Nakajima K, Kinuya S, Konishi S, Michigishi T, Aburano T, Tonami N. Preoperative assessment of residual hepatic functional reserve using99mTc-DTPA-galactosyl-human serum albumin dynamic SPECT. J Nucl Med 1999; 40:1644–1651.PubMedGoogle Scholar
  9. 9.
    Mitomo, Tsunoda T, Nakamura K, Kuwabara H. Quantification of intrahepatic non-uniform distributions for assessing impaired function of liver using99mTc-DTPA-galactosyl serum albumin liver SPECT scintigraphy. Nucl Med Commun 2001; 22:505–512.CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag 2003

Authors and Affiliations

  1. 1.Mallinckrodt Institute of Radiology and the Alvin J. Siteman Cancer CenterWashington University School of MedicineSt. LouisUSA

Personalised recommendations