Skeletal Radiology

, Volume 26, Issue 3, pp 167–172 | Cite as

Liposarcoma of soft tissue: MRI findings with pathologic correlation

  • Remide Arkun
  • Aysenur Memis
  • Taner Akalin
  • Esin Emin Ustun
  • Dundar Sabah
  • Gulsen Kandiloglu



To evaluate the MRI findings of liposarcomas of different histologic types and correlate these with the histopathologic features.


The MR images of seven liposarcomas were reviewed retrospectively to assess the tumor size, location, margination, signal characteristics and enhancement patterns in different histologic types.


Seven liposarcomas comprising three well-differentiated, two myxoid and two pleomorphic types were evaluated.

Results and conclusion

All tumors showed well-defined and mostly lobulated margins. The well-differentiated liposarcomas were composed mainly of fat with septations or nodules, were hyperintense on T2-weighted images, and demonstrated faint enhancement or no enhancement following intravenous contrast. Myxoid liposarcomas were homogeneous or mildly heterogeneous and a pseudocapsule was present in one case. Pleomorphic types showed a markedly heterogeneous internal structure. Both myxoid and pleomorphic lesions-showed moderate or marked heterogeneous enhancement after contrast administration. Well-differentiated liposarcomas may be differentiated from other types of the tumor by their largely lipomatous appearance. The malignancy grade increases in parallel with tumor heterogeneity and contrast enhancement.

Key words

Soft tissue, neoplasms Liposarcoma MRI, tissue characterization 


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  1. 1.
    Reszel PA, Soule EH, Coventry MB. Liposarcoma of the extremities and limb girdles: A study of 222 cases. J Bone Joint Surg [Am] 1966; 48: 229–244.CrossRefGoogle Scholar
  2. 2.
    Enzinger FM, Weiss SW. Soft tissue tumors. 2nd ed. St Louis: Mosby Year Book; 1988: 346–382.Google Scholar
  3. 3.
    Kransdorf MJ, Moser RP, Meis JM, Meyer CA. Fat containing soft tissue masses of the extremities. Radiographics 1991; 11:81–106.CrossRefGoogle Scholar
  4. 4.
    Reitan JB, Kaalhus O, Breenhovd IO, Sager EM, Stenwig AE, Talle K. Prognostic factors in liposarcoma. Cancer 1985; 55: 2482–2490.CrossRefGoogle Scholar
  5. 5.
    Edland RW. Liposarcoma: a retrospective study of fifteen cases, a review of the literature and a discussion of radiosensitivity. AJR 1968; 103: 778–791.CrossRefGoogle Scholar
  6. 6.
    Berquist TH, Ehman RL, King BF, et al. Value of MR imaging in differentiating benign from malignant soft-tissue masses: study of 95 lesions. AJR 1990; 155: 1251–1255.CrossRefGoogle Scholar
  7. 7.
    Demas BE, Heelan RT, Lane J et al. Soft tissue sarcomas of the extremities: comparison of MR and CT in determining the extent of disease. AJR 1988; 150: 615–620.CrossRefGoogle Scholar
  8. 8.
    Kransdorf MJ, Jelinek JS, Moser RP et al. Soft tissue masses: diagnosis using MR imaging. AJR 1989; 153: 541–547.CrossRefGoogle Scholar
  9. 9.
    Stoller DW. Magnetic resonance imaging in orthopaedics and sports medicine. Philadelphia: JB Lippincott, 1983: 1092–1094.Google Scholar
  10. 10.
    Jelinek JS, Kransdorf MJ, Shmookler BM, Aboulafia AJ, Malawer MM. Liposarcoma of the extremities: MR and CT findings in the histologic subtypes. Radiology 1993; 186: 455–459.CrossRefGoogle Scholar
  11. 11.
    Evans HL, Soule EH, Winkelman RK. Atypical lipoma, atypical intramuscular lipoma, and well differentiated retroperitoneal liposarcoma. Cancer 1979; 43: 574.CrossRefGoogle Scholar
  12. 12.
    Dooms GC, Hricak H, Sollitto RA, Higgins CB. Lipomatous tumors and tumors with fatty component: MR imaging potential and comparison of MR and CT results. Radiology 1985; 157: 479–483.CrossRefGoogle Scholar
  13. 13.
    Sundaram M, McGuire MH, Herbold DR, Beshany S, Fletcher J. High signal intensity soft tissue masses on Tl-weighted pulsing sequences. Skeletal Radiol 1987; 16: 30–35.CrossRefGoogle Scholar
  14. 14.
    Sundaram M, Baran G, Merenda G, McDonald DJ. Myxoid liposarcoma: magnetic resonance imaging appearance with clinical and histologic correlation. Skeletal Radiol 1990; 19: 359–362.CrossRefGoogle Scholar

Copyright information

© International Skeletal Society 1997

Authors and Affiliations

  • Remide Arkun
    • 1
  • Aysenur Memis
    • 1
  • Taner Akalin
    • 2
  • Esin Emin Ustun
    • 1
  • Dundar Sabah
    • 3
  • Gulsen Kandiloglu
    • 2
  1. 1.Department of RadiologyHospital of Ege UniversityBornovaTurkey
  2. 2.Department of PathologyHospital of Ege UniversityBornovaTurkey
  3. 3.Department of Orthopedic SurgeryHospital of Ege UniversityBornovaTurkey

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