Myoepithelial carcinoma of tibia mimic giant cell tumor: a case report with emphasis on MR features

  • Chien-Hung Lin
  • Kun-Yu Wu
  • Clement Kuen-Huang Chen
  • Chien-Feng Li
  • Tsyh-Jyi HsiehEmail author
Case Report


Intraosseous myoepithelial carcinoma is an extremely rare type of bone tumor that most often presents in the long tubular bones, but also occurs in small tubular bones and the axial skeleton. We report the radiographic images and complete magnetic resonance (MR) features of a 44-year-old male with right knee pain of 7 months’ duration. The radiographic findings and convention MR images indicated a giant cell tumor of the bone. The dynamic contrast-enhanced images showed a patent with the early wash-in and early wash-out usually noted in a giant cell tumor of the bone. Only water restriction on diffusion-weighted imaging (DWI) showed the malignant impression. Care should be taken when conventional images indicate giant cell tumor of the bone, as intraosseous myoepithelial carcinoma, although rare, can mimic this more common diagnosis. Further studies with DWI are warranted.


Intraosseous myoepithelial carcinoma MRI Diffusion-weighted imaging 


Compliance with ethical standards

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The study was approved by our Institutional Review Board, and the requirement of informed consent was waived.

Conflict of interest

The authors declare that they have no conflicts of interest.


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Copyright information

© ISS 2019

Authors and Affiliations

  1. 1.Department of Medical ImagingChi Mei Medical CenterTainan CityTaiwan
  2. 2.Department of Medical ImagingChi Mei HospitalTainanTaiwan
  3. 3.Department of BiotechnologySouthern Taiwan University of Science and TechnologyTainanTaiwan
  4. 4.Departments of PathologyChi Mei Medical CenterTainanTaiwan
  5. 5.National Institute of Cancer ResearchNational Health Research InstitutesZhunanTaiwan

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