Myxofibrosarcoma: First report of myxofibrosarcoma of bone arising at a bone infarct
Approximately 3300 new primary bone tumors will present to American physicians this year. This small but important group of malignancies has become more defined with developments in pathologic morphology, immunohistochemistry, and molecular studies. As tumor types are better partitioned, their specific characteristics are more readily observed. In this article we present the first reported case of a myxofibrosarcoma of bone developing within a bone infarct. With improved delineation of rarer tumor types, it is expected that additional cases of myxofibrosarcoma of bone will be recognized, potentially arising from a bone infarct. By framing the context, describing the case, and sharing pertinent figures, we hope to facilitate this recognition.
Compliance with ethical standards
Sources of support
The views expressed in the submitted article are not an official position of the institution or funder.
Conflict of interest
The authors declare that they have no conflict of interest.
- 8.Romeo S, Bovée JV, Kroon HM, Tirabosco R, Natali C, Zanatta L, et al. Malignant fibrous histiocytoma and fibrosarcoma of bone: a re-assessment in the light of currently employed morphological, immunohistochemical and molecular approaches. Virchows Arch. 2012;461(5):561–70.CrossRefPubMedGoogle Scholar
- 9.Fletcher CDM, Bridge JA, Hogendoorn PCW, Mertens F. WHO classification of tumours of soft tissue and bone. 4th ed. Lyon: IARC Press; 2013.Google Scholar
- 11.Goldblum JR, Folpe AL, Weiss SW. Enzinger and Weiss’s soft tissue tumors. 6th ed. Philadelphia: Elsevier/Saunders; 2014.Google Scholar