Skeletal Radiology

, Volume 44, Issue 3, pp 451–455 | Cite as

Gemcitabine-induced radiation recall myositis

  • Joshua Adam DelavanEmail author
  • Junzo P. Chino
  • Emily N. Vinson
Case Report


Radiation recall is an uncommon phenomenon in which administration of a chemotherapeutic agent induces an acute inflammatory reaction in previously irradiated tissues, often weeks to years after completion of radiotherapy. This entity is well known to medical and radiation oncologists, however only three cases have been reported in radiology journals. We present a case of gemcitabine-induced radiation recall that manifested as myositis with associated dermatitis in the posterior thigh of a patient with remote history of localized radiotherapy for biopsy-proven breast cancer metastasis. We also present a brief literature review to update the topic of radiation recall in imaging, and emphasize the importance of knowledge of this phenomenon when considering the differential diagnosis of myositis/dermatitis in a patient who has received cancer treatment.


Radiation recall Myositis Gemcitabine 


Conflict of interest

The authors declare they have no conflicts of interest.


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Copyright information

© ISS 2014

Authors and Affiliations

  • Joshua Adam Delavan
    • 1
    Email author
  • Junzo P. Chino
    • 2
  • Emily N. Vinson
    • 1
  1. 1.Department of RadiologyDuke University Medical CenterDurhamUSA
  2. 2.Department of Radiation OncologyDuke University Medical CenterDurhamUSA

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