Skeletal Radiology

, Volume 41, Issue 3, pp 357–360 | Cite as

Magnetic resonance imaging appearance of scurvy with gelatinous bone marrow transformation

  • Christopher M. Brennan
  • Kristen A. Atkins
  • Colleen H. Druzgal
  • Cree M. Gaskin
Case Report


Scurvy is a lethal but treatable disease that is rare in industrialized countries. Caused by vitamin C deficiency, it is most prevalent in persons of low socioeconomic status and smokers. Low levels of circulating vitamin C result in poor collagen fiber formation that, in turn, leads to demineralized bones, microfractures, and poor healing. Here we report a case of scurvy in a 5-year-old boy with normal radiographs in whom initial concern for leukemia based upon magnetic resonance imaging and clinical presentation led to a bone marrow biopsy revealing gelatinous transformation.


Scurvy Vitamin C Malnutrition Magnetic resonance imaging Serous atrophy Gelatinous transformation 


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Copyright information

© ISS 2012

Authors and Affiliations

  • Christopher M. Brennan
    • 1
  • Kristen A. Atkins
    • 3
  • Colleen H. Druzgal
    • 4
  • Cree M. Gaskin
    • 1
    • 2
  1. 1.Department of Radiology and Medical ImagingUniversity of Virginia Health SystemCharlottesvilleUSA
  2. 2.Department of Orthopaedic SurgeryUniversity of Virginia Health SystemCharlottesvilleUSA
  3. 3.Department of PathologyUniversity of Virginia Health SystemCharlottesvilleUSA
  4. 4.Department of PediatricsUniversity of Virginia Health SystemCharlottesvilleUSA

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