Skeletal Radiology

, 40:1375 | Cite as

Primary synovial chondrosarcoma of the hip joint in a 45-year-old male: case report and literature review

  • Leon David Rybak
  • Lubna Khaldi
  • James Wittig
  • German C. Steiner
Case Report


Synovial chondrosarcoma is a rare tumor, seen most commonly arising from antecedent synovial chondromatosis, the more common benign entity. The distinction between the two can be difficult on the basis of clinical, imaging, and histologic criteria. The authors report a case of pathologically proven synovial chondrosarcoma of the hip in a 45-year-old male initially treated for presumed synovial chondromatosis. The case is made more unusual by the fact that no evidence of co-existent synovial chondromatosis was noted at histology. The literature as regards synovial chondrosarcoma, both de novo and secondary cases, is reviewed.


Synovial chondrosarcoma Synovial chondromatosis Intraarticular soft tissue mass MRI Histology 


  1. 1.
    Bertoni F, Unni KK, Beabout JW, Sim FH. Chondrosarcomas of the synovium. Cancer. 1991;67(1):155–62.PubMedCrossRefGoogle Scholar
  2. 2.
    Wenger DE, Sundaram M, Unni KK, Janney CG, Merkel K. Acral synovial chondrosarcoma. Skeletal Radiol. 2002;31(2):125–9.PubMedCrossRefGoogle Scholar
  3. 3.
    Kenan S, Abdelwahab IF, Klein MJ, Lewis MM. Case report 817: synovial chondrosarcoma secondary to synovial chondromatosis. Skeletal Radiol. 1993;22(8):623–6.PubMedCrossRefGoogle Scholar
  4. 4.
    Ichikawa T, Miyauchi M, Nikai H, Yoshiga K. Synovial chondrosarcoma arising in the temporomandibular joint. J Oral Maxillofac Surg. 1998;56(7):890–4.PubMedCrossRefGoogle Scholar
  5. 5.
    Bhadra AK, Pollock R, Tirabosco RP, Skinner JA, Cannon SR, Briggs TW, et al. Primary tumours of the synovium. A report of four cases of malignant tumour. J Bone Joint Surg Br. 2007;89(11):1504–8.PubMedCrossRefGoogle Scholar
  6. 6.
    Davis RI, Hamilton A, Biggart JD. Primary synovial chondromatosis: a clinicopathologic review and assessment of malignant potential. Hum Pathol. 1998;29(7):683–8.PubMedCrossRefGoogle Scholar
  7. 7.
    Murphey MD, Vidal JA, Fanburg-Smith JC, Gajewski DA. Imaging of synovial chondromatosis with radiologic-pathologic correlation. Radiographics. 2007;27(5):1465–88.PubMedCrossRefGoogle Scholar
  8. 8.
    Anract P, Katabi M, Forest M, Benoit J, Witvoet J, Tomeno B. Synovial chondromatosis and chondrosarcoma. A study of the relationship between these two diseases. Rev Chir Orthop Reparatrice Appar Mot. 1996;82(3):216–24.PubMedGoogle Scholar
  9. 9.
    Campanacci DA, Matera D, Franchi A, Capanna R. Synovial chondrosarcoma of the hip: report of two cases and literature review. Chir Organi Mov. 2008;92(3):139–44.PubMedCrossRefGoogle Scholar
  10. 10.
    Kindblom LG, Angervall L. Myxoid chondrosarcoma of the synovial tissue. A clinicopathologic, histochemical, and ultrastructural analysis. Cancer. 1983;52(10):1886–95.PubMedCrossRefGoogle Scholar
  11. 11.
    Scully RE, Mark EJ, McNeely WF, McNeely BU. Extra-skeletal myxoid chondrosarcoma of synovium of knee joint. Case records of the Massachusetts General Hospital. N Engl J Med. 1991;326(19):1361–7.Google Scholar
  12. 12.
    Zamora EE, Mansor A, Vanel D, Errani C, Mercuri M, Picci P, et al. Synovial chondrosarcoma: report of two cases and literature review. Eur J Radiol. 2009;72(1):38–43.PubMedCrossRefGoogle Scholar
  13. 13.
    Taconis WK, van der Heul RO, Taminiau AM. Synovial chondrosarcoma: report of a case and review of the literature. Skeletal Radiol. 1997;26(11):682–5.PubMedCrossRefGoogle Scholar
  14. 14.
    Wittkop B, Davies AM, Mangham DC. Primary synovial chondromatosis and synovial chondrosarcoma: a pictorial review. Eur Radiol. 2002;12(8):2112–9.PubMedGoogle Scholar
  15. 15.
    Sperling BL, Angel S, Stoneham G, Chow V, McFadden A, Chibbar R. Synovial chondromatosis and chondrosarcoma: a diagnostic dilemma. Sarcoma. 2003;7(2):69–73.PubMedCrossRefGoogle Scholar
  16. 16.
    Norman A, Steiner GC. Bone erosion in synovial chondromatosis. Radiology. 1986;161(3):749–52.PubMedGoogle Scholar
  17. 17.
    Sah AP, Geller DS, Mankin HJ, Rosenberg AE, Delaney TF, Wright CD, et al. Malignant transformation of synovial chondromatosis of the shoulder to chondrosarcoma. A case report. J Bone Joint Surg Am. 2007;89(6):1321–8.PubMedCrossRefGoogle Scholar

Copyright information

© ISS 2011

Authors and Affiliations

  • Leon David Rybak
    • 1
  • Lubna Khaldi
    • 2
  • James Wittig
    • 3
  • German C. Steiner
    • 4
  1. 1.Department of RadiologyNYU Hospital for Joint DiseasesNew YorkUSA
  2. 2.Department of HistopathologyUniversity Hospital of LarissaLarissaGreece
  3. 3.Department of Orthopaedic SurgeryMount Sinai Hospital Medical CenterNew YorkUSA
  4. 4.Department of Pathology and Laboratory MedicineNYU Hospital for Joint DiseasesNew YorkUSA

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