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Skeletal Radiology

, Volume 36, Supplement 1, pp 34–37 | Cite as

Radiography of successful bone marrow transplantation for osteopetrosis

  • Colleen M. Costelloe
  • Farzin Eftekhari
  • Demetrios Petropoulos
Case Report

Abstract

Hematopoietic stem cell transplantation (HSCT) is the only curative therapy for autosomal recessive infantile malignant osteopetrosis, an otherwise fatal disease. HSCT has also been utilized in patients with the less severe autosomal recessive intermediate form in an attempt to correct hematologic abnormalities and halt cranial nerve deficits caused by progressive cranial foraminal stenosis. Successful engraftment is accompanied by rapid normalization of radiographic signs of osteopetrosis.

Keywords

Osteopetrosis Bone marrow transplant Radiography Imaging 

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Copyright information

© ISS 2006

Authors and Affiliations

  • Colleen M. Costelloe
    • 1
    • 3
  • Farzin Eftekhari
    • 1
  • Demetrios Petropoulos
    • 2
  1. 1.Division of Diagnostic Imaging, Department of Diagnostic RadiologyUniversity of Texas M.D. Anderson Cancer CenterHoustonUSA
  2. 2.Department of PediatricsUniversity of Texas M.D. Anderson Cancer CenterHoustonUSA
  3. 3.Musculoskeletal Section, Division of Diagnostic Imaging, Department of Diagnostic RadiologyUniversity of Texas M.D. Anderson Cancer CenterHoustonUSA

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