Advertisement

Skeletal Radiology

, Volume 33, Issue 4, pp 241–243 | Cite as

Osseous Kaposi sarcoma in an HIV-positive patient

  • Loukas ThanosEmail author
  • Sofia Mylona
  • Vasilios Kalioras
  • Maria Pomoni
  • Nikolaos Batakis
Case Report

Abstract

A case of osseous Kaposi sarcoma in a 35-year-old man is described. The patient (HIV-positive for 8 years) suffered from cutaneous Kaposi sarcoma and presented with right-sided chest pain. He underwent a chest CT scan that revealed three osteolytic lesions involving rib and vertebra with large soft tissue masses, without cutaneous lesions at these sites. CT-guided core needle biopsy led to a histological diagnosis of Kaposi sarcoma.

Keywords

Rib Kaposi sarcoma Lytic bone lesion HIV-positive CT-guided core needle biopsy 

References

  1. 1.
    Tappero JW, Conant MA, Wolfe SF, et al. Kaposi’s sarcoma. Epidemiology, pathogenesis, histology, clinical spectrum, staging criteria and therapy. J Am Acad Dermatol 1993; 28:371–395.PubMedGoogle Scholar
  2. 2.
    Mitsuyasu RT. Kaposi’s sarcoma in the acquired immunodeficiency syndrome. Infect Dis Clin North Am 1988; 2:511–523.PubMedGoogle Scholar
  3. 3.
    Garman ME. The cutaneous manifestations of HIV infection. Dermatol Clin 2002; 20:193–208.PubMedGoogle Scholar
  4. 4.
    Requena L, Sangueza OP. Cutaneous vascular proliferations. III. Malignant neoplasms, other cutaneous neoplasms with significant vascular component, and disorders erroneously considered as vascular neoplasms. J Am Acad Dermatol 1998; 38:143–178.PubMedGoogle Scholar
  5. 5.
    Meyers SA, Kuhlman JE, Fishman EK. Kaposi sarcoma involving bone: CT demonstration in a patient with AIDS. J Comput Assist Tomogr 1990; 14:161–162.PubMedGoogle Scholar
  6. 6.
    Lombardo M, Girolomoni G, Spina V, Zambruno G, Gianneti A. Kaposi’s sarcoma with primary bone lesions in an HIV-seronegative man. Br J Dermatol 1996; 134:966–969.CrossRefPubMedGoogle Scholar
  7. 7.
    Ritz-Guiliac L, Machet MC, Vedere V, Vaillant L, Lorette G. Bone involvement in a case of Kaposi sarcoma. Dermatology 1999; 198:73–74.CrossRefPubMedGoogle Scholar
  8. 8.
    Nguyen C, Lander P, Begin LR, Jarzem P, Grad R. AIDS-related Kaposi sarcoma involving the tarsal bones. Skeletal Radiol 1996; 25:100–102.CrossRefPubMedGoogle Scholar
  9. 9.
    Major NM, Tehranzadeh J. Musculoskeletal manifestations of AIDS. Radiol Clin North Am 1997; 35: 1181.Google Scholar
  10. 10.
    Teh BS, Lu HH, Lynch GR, Banez E, Kroll MH. AIDS-related Kaposi’s sarcoma involving bone and bone marrow. South Med J 1999; 92:61–64.PubMedGoogle Scholar
  11. 11.
    Hangge U, Ruzinca T, Tyring S, Stuschke M, Roggendorf M, Schwartz R, Seeber S. Update on Kaposi’s sarcoma and other HHV8 associated diseases. 1. Epidemiology, environmental predispositions, clinical manifestations, and therapy. Lancet Infect Dis 2002;2:281–292.CrossRefPubMedGoogle Scholar
  12. 12.
    Isenbarger DW, Aronson NE. Lytic vertebral lesions: an unusual manifestation of AIDS-associated Kaposi’s sarcoma. Clin Infect Dis1994; 19:751–755.Google Scholar
  13. 13.
    O’Connor PG. AIDS oncology. Infect Dis Clin North Am 2000; 14:945–965.PubMedGoogle Scholar
  14. 14.
    Le Boit P, Berger T, Egbert B, Beckstead J, Benedict Yen TS, Stoler M. Bacillary angiomatosis: the histopathology and differential diagnosis of a pseudoneoplastic infection in patients with human immunodeficiency virus disease. Am J Surg Pathol 1989; 13:909–920.PubMedGoogle Scholar
  15. 15.
    Hallet Y, Van Overschelde J. An unusual localization and presentation of Kaposi’s sarcoma. Acta Orthop Belg 1999; 65:109–112.Google Scholar
  16. 16.
    Steinbach LS, Tehranzadeh J, Fleckenstein JL, Vanarthos WJ, Pais MJ. Human immunodeficiency virus infections. Musculoskeletal manifestations. Radiology 1993; 186:833–838.PubMedGoogle Scholar
  17. 17.
    Ensoli B, Barillari G, Gallo RC. Cytokines and growth factors in the pathogenesis of AIDS-associated Kaposi’s sarcoma. Immunol Rev 1992; 127:147–155.PubMedGoogle Scholar
  18. 18.
    Wanarthos WJ, Ganz WI, Vanarthos JC, Serafini AN, Tebranzadeb J. Diagnostic uses of nuclear medicine in AIDS. Radiographics 1992; 12:731–749.PubMedGoogle Scholar

Copyright information

© ISS 2004

Authors and Affiliations

  • Loukas Thanos
    • 1
    Email author
  • Sofia Mylona
    • 1
  • Vasilios Kalioras
    • 1
  • Maria Pomoni
    • 1
  • Nikolaos Batakis
    • 1
  1. 1.Radiology Department“Korgialeneio-Benakeio”, Red Cross Hospital of AthensAthensGreece

Personalised recommendations