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Applied Microbiology and Biotechnology

, Volume 57, Issue 4, pp 451–459 | Cite as

Biotechnological production of pyruvic acid

  •  Y. Li
  •  J. Chen
  •  S.-Y. Lun
Mini-Review

Abstract.

Pyruvic acid is an important organic acid widely used in the chemical and drug, as well as agrochemical, industries. Compared with the chemical method, biotechnological production of pyruvic acid is an alternative approach because of the low cost. An overview of biotechnological production of pyruvate, including direct fermentative production employing eukaryotic and prokaryotic microorganisms, production by a resting cell method and an enzymatic method as well as the recovery of pyruvate, is discussed. A multi-vitamin auxotrophic yeast strain, Torulopsis glabrata, has been used in the commercial production of pyruvate; emphasis is therefore placed on the mechanism and characteristics of pyruvate production by this strain.

Keywords

Pyruvate Organic Acid Chemical Method Commercial Production Yeast Strain 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 2001

Authors and Affiliations

  •  Y. Li
    • 1
  •  J. Chen
    • 1
  •  S.-Y. Lun
    • 1
  1. 1.Key Laboratory of Industrial Biotechnology, Ministry of Education, Southern Yangtze University, Huihe Road, No. 170, Wuxi, 214036, P.R. China

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