Applied Microbiology and Biotechnology

, Volume 102, Issue 10, pp 4305–4318 | Cite as

Wound healing applications of biogenic colloidal silver and gold nanoparticles: recent trends and future prospects

  • Muhammad OvaisEmail author
  • Irshad Ahmad
  • Ali Talha Khalil
  • Sudip Mukherjee
  • Rabia Javed
  • Muhammad Ayaz
  • Abida Raza
  • Zabta Khan Shinwari


Nanotechnology has emerged as a prominent scientific discipline in the technological revolution of this millennium. The scientific community has focused on the green synthesis of metal nanoparticles as compared to physical and chemical methods due to its eco-friendly nature and high efficacy. Medicinal plants have been proven as the paramount source of various phytochemicals that can be used for the biogenic synthesis of colloidal silver and gold nanoparticles as compared to other living organisms, e.g., microbes and fungi. According to various scientific reports, the biogenic nanoparticles have shown promising potential as wound healing agents. However, not a single broad review article was present that demonstrates the wound healing application of biogenic silver and gold nanoparticles. Foreseeing the overall literature published, we for the first time intended to discuss the current trends in wound healing via biogenic silver and gold nanoparticles. Furthermore, light has been shed on the mechanistic aspects of wound healing along with futuristic discussion on the faith of biogenic silver and gold nanoparticles as potential wound healing agents.


Wound healing Phytonanotechnology Silver nanoparticles Gold nanoparticles Green synthesis Nanomedicine 



This work is funded by PAK-NORWAY Institutional Cooperation Program, PK3004, and COMSTECH-TWAS project reference number (12-198 RG/PHA/AS_C-UNESCO FR: 3240270874).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This article does not contain any studies with animals or human participants performed by any of the authors.


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© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Biotechnology, Faculty of Biological SciencesQuaid-i-Azam UniversityIslamabadPakistan
  2. 2.National Institute of Lasers and OptronicsPakistan Atomic Energy CommissionIslamabadPakistan
  3. 3.Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijingChina
  4. 4.Department of Life SciencesKing Fahd University of Petroleum and Minerals (KFUPM)DhahranSaudi Arabia
  5. 5.Department of Eastern Medicine and SurgeryQarshi UniversityLahorePakistan
  6. 6.Department of BioengineeringRice UniversityHoustonUSA
  7. 7.Department of PharmacyUniversity of MalakandChakdaraPakistan
  8. 8.Pakistan Academy of Sciences (PAS)IslamabadPakistan

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