Applied Microbiology and Biotechnology

, Volume 101, Issue 23–24, pp 8309–8319 | Cite as

Potential applications of biosurfactant rhamnolipids in agriculture and biomedicine

  • Jianwei Chen
  • Qihao Wu
  • Yi Hua
  • Jun Chen
  • Huawei Zhang
  • Hong WangEmail author


Rhamnolipids have recently emerged as promising bioactive molecules due to their novel structures, diverse and versatile biological functions, lower toxicity, higher biodegradability, as well as production from renewable resources. The advantages of rhamnolipids make them attractive targets for research in a wide variety of applications. Especially rhamnolipids are likely to possess potential applications of the future in areas such as biomedicine, therapeutics, and agriculture. The purpose of this mini review is to provide a comprehensive prospective of biosurfactant rhamnolipids as potential antimicrobials, immune modulators, and virulence factors, and anticancer agents in the field of biomedicine and agriculture that may meet the ever-increasing future pharmacological treatment and food safety needs in human health.


Rhamnolipids Application Agriculture and biomedicine 



The authors thank Michael J. Murphy, Ph.D., for his suggestions in this manuscript.

Funding information

This project was supported by National Natural Science Foundation of China (No. 81773628 and No. 41776139), National Natural Science Foundation of China (Key Program) (No. 21337005), and Zhejiang Provincial Natural Science Foundation (No. LY16H300008 and No. LY16H300007).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no competing interests.

Ethical standards

This article does not contain any studies with human participants or animals performed by any of the authors.


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Copyright information

© Springer-Verlag GmbH Germany 2017

Authors and Affiliations

  • Jianwei Chen
    • 1
  • Qihao Wu
    • 1
  • Yi Hua
    • 1
  • Jun Chen
    • 1
  • Huawei Zhang
    • 1
  • Hong Wang
    • 1
    • 2
    Email author
  1. 1.College of Pharmaceutical ScienceZhejiang University of TechnologyHangzhouChina
  2. 2.Collaborative Innovation Center of Yangtze River Delta Region Green PharmaceuticalsZhejiang University of TechnologyHangzhouChina

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