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Applied Microbiology and Biotechnology

, Volume 101, Issue 3, pp 905–919 | Cite as

Versatility of hydrocarbon production in cyanobacteria

  • Min Xie
  • Weihua WangEmail author
  • Weiwen Zhang
  • Lei Chen
  • Xuefeng LuEmail author
Mini-Review

Abstract

Cyanobacteria are photosynthetic microorganisms using solar energy, H2O, and CO2 as the primary inputs. Compared to plants and eukaryotic microalgae, cyanobacteria are easier to be genetically engineered and possess higher growth rate. Extensive genomic information and well-established genetic platform make cyanobacteria good candidates to build efficient biosynthetic pathways for biofuels and chemicals by genetic engineering. Hydrocarbons are a family of compounds consisting entirely of hydrogen and carbon. Structural diversity of the hydrocarbon family is enabled by variation in chain length, degree of saturation, and rearrangements of the carbon skeleton. The diversified hydrocarbons can be used as valuable chemicals in the field of food, fuels, pharmaceuticals, nutrition, and cosmetics. Hydrocarbon biosynthesis is ubiquitous in bacteria, yeasts, fungi, plants, and insects. A wide variety of pathways for the hydrocarbon biosynthesis have been identified in recent years. Cyanobacteria may be superior chassis for hydrocabon production in a photosynthetic manner. A diversity of hydrocarbons including ethylene, alkanes, alkenes, and terpenes can be produced by cyanobacteria. Metabolic engineering and synthetic biology strategies can be employed to improve hydrocarbon production in cyanobacteria. This review mainly summarizes versatility and perspectives of hydrocarbon production in cyanobacteria.

Keywords

Hydrocarbon Ethylene Terpene Alkane Cyanobacteria Metabolic engineering 

Notes

Acknowledgements

This work was supported by the National Science Fund for Distinguished Young Scholars of China (31525002 to X. Lu), the Shandong Taishan Scholarship (X. Lu), the Excellent Youth Award of the Shandong Natural Science Foundation (JQ201306 to X. Lu), the Innovation Leading Talent of Qingdao (15-10-3-15-(31)-zch to X. Lu), SINO-GERMAN Research Project (GZ 877 to X. Lu), and the National Natural Science Foundation of China (31300036 to W. Wang).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

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© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  1. 1.Laboratory of Synthetic Microbiology, School of Chemical Engineering and TechnologyTianjin UniversityTianjinPeople’s Republic of China
  2. 2.Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess TechnologyChinese Academy of SciencesQingdaoPeople’s Republic of China
  3. 3.Shandong Provincial Key Laboratory of Energy Genetics, Qingdao Institute of Bioenergy and Bioprocess TechnologyChinese Academy of SciencesQingdaoPeople’s Republic of China
  4. 4.Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess TechnologyChinese Academy of SciencesQingdaoPeople’s Republic of China

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