Applied Microbiology and Biotechnology

, Volume 99, Issue 4, pp 1571–1586 | Cite as

Antimicrobial compounds from seaweeds-associated bacteria and fungi

  • Ravindra Pal SinghEmail author
  • Puja Kumari
  • C. R. K. ReddyEmail author


In recent decade, seaweeds-associated microbial communities have been significantly evaluated for functional and chemical analyses. Such analyses let to conclude that seaweeds-associated microbial communities are highly diverse and rich sources of bioactive compounds of exceptional molecular structure. Extracting bioactive compounds from seaweed-associated microbial communities have been recently increased due to their broad-spectrum antimicrobial activities including antibacterial, antifungal, antiviral, anti-settlement, antiprotozoan, antiparasitic, and antitumor. These allelochemicals not only provide protection to host from other surrounding pelagic microorganisms, but also ensure their association with the host. Antimicrobial compounds from marine sources are promising and priority targets of biotechnological and pharmaceutical applications. This review describes the bioactive metabolites reported from seaweed-associated bacterial and fungal communities and illustrates their bioactivities. Biotechnological application of metagenomic approach for identifying novel bioactive metabolites is also dealt, in view of their future development as a strong tool to discover novel drug targets from seaweed-associated microbial communities.


Biotechnological application Seaweed Antibacterial Antifungal Antifouling Bioactive compounds Metagenomics 



CSIR is gratefully acknowledged for awarding the Senior Research Fellowship (SRF) to R.P. Singh and P. Kumari. CSIR-CSMCRI also thanked for facilities and encouragement provided while preparing this manuscript.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Discipline of Marine Biotechnology and EcologyCSIR—Central Salt and Marine Chemicals Research InstituteBhavnagarIndia
  2. 2.Laboratory of Microbial Technology, Department of Bioscience and Biotechnology, Faculty of AgricultureKyushu UniversityFukuokaJapan
  3. 3.Institute of Plant SciencesAgricultural Research Organization (ARO), Volcani CenterBet DaganIsrael
  4. 4.Academy of Scientific and Innovative Research (AcSIR)New DelhiIndia

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