The effect of a disrupted yhjQ gene on cellular morphology and cell growth in Escherichia coli
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The 5′ upstream region of the cellulose synthase operon (bcs operon) has been isolated by cloning from Escherichia coli. A gene encoding YhjQ is located 1.0 kb upstream of the bcs operon in E. coli. The function of YhjQ remains unknown. Insertional inactivation of the yhjQ gene causes abnormal cell division, resulting in incomplete partition of the chromosome and filamentous cells of various sizes. These results suggest that the product of yhjQ may affect normal doubling and cellular morphology.
KeywordsEscherichia Coli Cellulose Cell Growth Cell Division Upstream Region
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