Advertisement

Applied Microbiology and Biotechnology

, Volume 59, Issue 2–3, pp 143–152 | Cite as

Biotechnology and bioremediation: successes and limitations

  •  M. Dua
  •  A. Singh
  •  N. Sethunathan
  •  A. Johri
Mini-Review

Abstract.

With advances in biotechnology, bioremediation has become one of the most rapidly developing fields of environmental restoration, utilizing microorganisms to reduce the concentration and toxicity of various chemical pollutants, such as petroleum hydrocarbons, polycyclic aromatic hydrocarbons, polychlorinated biphenyls, phthalate esters, nitroaromatic compounds, industrial solvents, pesticides and metals. A number of bioremediation strategies have been developed to treat contaminated wastes and sites. Selecting the most appropriate strategy to treat a specific site can be guided by considering three basic principles: the amenability of the pollutant to biological transformation to less toxic products (biochemistry), the accessibility of the contaminant to microorganisms (bioavailability) and the opportunity for optimization of biological activity (bioactivity). Recent advances in the molecular genetics of biodegradation and studies on enzyme-tailoring and DNA-shuffling are discussed in this paper.

Keywords

Toxicity Petroleum Hydrocarbon Polycyclic Aromatic Hydrocarbon Biodegradation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Copyright information

© Springer-Verlag 2002

Authors and Affiliations

  •  M. Dua
    • 1
  •  A. Singh
    • 2
  •  N. Sethunathan
    • 3
  •  A. Johri
    • 1
  1. 1.Department of Zoology, University of Delhi, Delhi 110007, India
  2. 2.Department of Biology, University of Waterloo, Waterloo, N2L 3G1, Ontario, Canada
  3. 3.CSIRO Land and Water, PMB 2, Glen Osmond, SA 5064, Australia

Personalised recommendations