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Bdellovibrio and Like Organisms Are Predictors of Microbiome Diversity in Distinct Host Groups

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Abstract

Biodiversity is generally believed to be a main determinant of ecosystem functioning. This principle also applies to the microbiome and could consequently contribute to host health. According to ecological theory, communities are shaped by top predators whose direct and indirect interactions with community members cause stability and diversity. Bdellovibrio and like organisms (BALOs) are a neglected group of predatory bacteria that feed on Gram-negative bacteria and can thereby influence microbiome composition. We asked whether BALOs can predict biodiversity levels in microbiomes from distinct host groups and environments. We demonstrate that genetic signatures of BALOs are commonly found within the 16S rRNA reads from diverse host taxa. In many cases, their presence, abundance, and especially richness are positively correlated with overall microbiome diversity. Our findings suggest that BALOs can act as drivers of microbial alpha-diversity and should therefore be considered candidates for the restoration of microbiomes and the prevention of dysbiosis.

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Acknowledgments

We are grateful for advice from members of the Schulenburg group and the Collaborative Research Center CRC1182 on Origin and Function of Metaorganisms.

Funding

This work was funded by the CRC1182, projects A4 and B2.

Author information

Authors and Affiliations

  1. Department of Evolutionary Ecology and Genetics, Zoological Institute, CAU Kiel, Am Botanischen Garten 1-9, 24118, Kiel, Germany

    Julia Johnke & Hinrich Schulenburg

  2. Department of Cell and Developmental Biology, Zoological Institute, CAU Kiel, Am Botanischen Garten 1-9, 24118, Kiel, Germany

    Sebastian Fraune & Thomas C. G. Bosch

  3. RD3 Marine Microbiology, GEOMAR Helmholtz Centre for Ocean Research Kiel, Düsternbrooker Weg 20, 24105, Kiel, Germany

    Ute Hentschel

  4. Section of Marine Biology, CAU Kiel, Am Botanischen Garten 1-9, 24118, Kiel, Germany

    Ute Hentschel

Authors
  1. Julia Johnke
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  2. Sebastian Fraune
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  3. Thomas C. G. Bosch
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  4. Ute Hentschel
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  5. Hinrich Schulenburg
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Corresponding author

Correspondence to Hinrich Schulenburg.

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Conflict of Interest

The authors declare that they have no conflict of interest.

Data Availability

The nucleotide sequence data reported are available in the EMBL databases under the accession number PRJEB30476.

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Johnke, J., Fraune, S., Bosch, T. et al. Bdellovibrio and Like Organisms Are Predictors of Microbiome Diversity in Distinct Host Groups. Microb Ecol 79, 252–257 (2020). https://doi.org/10.1007/s00248-019-01395-7

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  • DOI: https://doi.org/10.1007/s00248-019-01395-7

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