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Microbial Ecology

, Volume 68, Issue 1, pp 24–34 | Cite as

Bacterial Signaling Ecology and Potential Applications During Aquatic Biofilm Construction

  • Leticia M. Vega
  • Pedro J. Alvarez
  • Robert J. C. McLeanEmail author
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Abstract

In their natural environment, bacteria and other microorganisms typically grow as surface-adherent biofilm communities. Cell signal processes, including quorum signaling, are now recognized as being intimately involved in the development and function of biofilms. In contrast to their planktonic (unattached) counterparts, bacteria within biofilms are notoriously resistant to many traditional antimicrobial agents and so represent a major challenge in industry and medicine. Although biofilms impact many human activities, they actually represent an ancient mode of bacterial growth as shown in the fossil record. Consequently, many aquatic organisms have evolved strategies involving signal manipulation to control or co-exist with biofilms. Here, we review the chemical ecology of biofilms and propose mechanisms whereby signal manipulation can be used to promote or control biofilms.

Keywords

Quorum Sense Homoserine Lactone Reporter Strain Acidithiobacillus Ferrooxidans Quorum Quenching 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

Work in the authors' laboratories has been funded by the Environmental Protection Agency (PJJ, RJCM), Norman Hackerman Advanced Research Program (RJCM), and an NSF cooperative agreement (HRD-0450363) (LMV). RJCM would like to thank Clay Fuqua for introducing him to the fascinating world of quorum signaling.

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Leticia M. Vega
    • 1
  • Pedro J. Alvarez
    • 1
  • Robert J. C. McLean
    • 2
    Email author
  1. 1.Department of Civil and Environmental EngineeringRice UniversityHoustonUSA
  2. 2.Department of BiologyTexas State UniversitySan MarcosUSA

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