Imaging surveillance for children with predisposition to renal tumors
Effective surveillance is necessary for early detection of tumors in children with cancer predisposition syndromes. Instituting a surveillance regimen in children comes with practical challenges that include determining imaging modality and timing, and considering cost efficiency, accessibility, and the significant consequences of false-positive and false-negative results. To address these challenges, the American Association for Cancer Research has recently published consensus recommendations that focus on surveillance of cancer predisposition syndromes in children. This review condenses the imaging surveillance recommendations for syndromes that carry a predisposition to renal tumors in childhood, and includes summaries of the predisposition syndromes and discussion of considerations of available imaging modalities.
KeywordsDICER1 syndrome Hepatoblastoma predisposition syndromes Kidney Li–Fraumeni syndrome Magnetic resonance imaging Tumor Ultrasound Von Hippel–Lindau syndrome Wilms tumor
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Conflicts of interest
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