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Pediatric Radiology

, Volume 46, Issue 12, pp 1694–1704 | Cite as

Imaging features of undifferentiated embryonal sarcoma of the liver: a series of 15 children

  • Flaviu GaborEmail author
  • Stephanie Franchi-Abella
  • Laura Merli
  • Catherine Adamsbaum
  • Daniele Pariente
Original Article

Abstract

Background

Undifferentiated embryonal sarcoma of the liver is a rare malignant mesenchymal tumour occurring mostly in children ages 6–10 years. The discrepancy between its solid appearance on US and cystic-like appearance on CT has been described.

Objective

To study the imaging particularities and similarities among our cases of undifferentiated embryonal sarcoma and to report the errors in initial diagnoses.

Materials and methods

We conducted a retrospective study of 15 children with undifferentiated embryonal sarcoma diagnosed or referred to our hospital during 1997–2015 and analysed the clinical, biological and imaging data.

Results

We identified eight boys and seven girls ages 9 months to 14 years. Ten children presented with abdominal pain. Alpha-fetoprotein was slightly increased in one. Initial US and CT had been performed for all, while additional MRI had been done in two children. Initial CT demonstrated a hypoattenuated mass in all. Rupture was seen in five and intratumoural bleeding in seven children. Tumour volumes reduced during neoadjuvant chemotherapy in 10 children.

Conclusion

Undifferentiated embryonal sarcoma might be suggested in a non-secreting unifocal tumour with well-defined borders, fluid-filled spaces on US, hypoattenuation and serpiginous vessels on CT, and if there are signs of internal bleeding or rupture on CT or MRI.

Keywords

Children Computed tomography Cystic mesenchymal tumour Liver tumour Magnetic resonance imaging Sarcoma Ultrasound 

Notes

Compliance with ethical standards

Conflicts of interest

None

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Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • Flaviu Gabor
    • 1
    Email author
  • Stephanie Franchi-Abella
    • 1
  • Laura Merli
    • 2
  • Catherine Adamsbaum
    • 1
    • 3
    • 4
  • Daniele Pariente
    • 1
  1. 1.Department of Pediatric RadiologyBicêtre HospitalLe Kremlin-BicêtreFrance
  2. 2.Unit of Hepato-Biliary and Transplant Surgery, Department of Surgery and Transplantation CentreBambino Gesù Children’s HospitalRomeItaly
  3. 3.Faculty of MedicineParis Sud UniversityLe Kremlin-BicêtreFrance
  4. 4.LTCI, CNRS, Télécom Paris TechUniversité Paris-SaclayParisFrance

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