Pediatric Radiology

, Volume 44, Issue 2, pp 202–211

Olive without a cause: the story of infantile hypertrophic pyloric stenosis

Historical Perspective

DOI: 10.1007/s00247-013-2834-7

Cite this article as:
Markowitz, R.I. Pediatr Radiol (2014) 44: 202. doi:10.1007/s00247-013-2834-7


For many diseases and medical conditions the clinical recognition and the development of accurate diagnostic methods and the etiological cause precede effective treatment. In the case of infantile hypertrophic pyloric stenosis (HPS), this sequence of events did not happen. Clinical recognition of the entity proceeded directly to the development of curative treatment. Reliable diagnostic imaging methods followed, but a definitive etiology has not been elucidated. This paper reviews the historical aspects of hypertrophic pyloric stenosis, discusses how and why it took so long for this not uncommon disease to be recognized, and highlights the physicians who changed an often fatal disease into an easily diagnosed and treated minor affliction.


Infantile hypertrophic pyloric stenosis History Diagnostic imaging Treatment Etiology Innovation Ultrasound Infant 

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.Department of Radiology, Perelman School of MedicineUniversity of PennsylvaniaPhiladelphiaUSA
  2. 2.Department of RadiologyChildren’s Hospital of PhiladelphiaPhiladelphiaUSA

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