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Pediatric Radiology

, Volume 43, Issue 11, pp 1444–1452 | Cite as

Sonographic and radiographic imaging features of the neonate with necrotizing enterocolitis: correlating findings with outcomes

  • Karl Muchantef
  • Monica Epelman
  • Kassa Darge
  • Haresh Kirpalani
  • Pablo Laje
  • Sudha A. Anupindi
Original Article

Abstract

Background

Abdominal radiography is the reference standard in imaging neonates with necrotizing enterocolitis (NEC); however, ultrasound of the abdomen including bowel may be of value in this setting.

Objective

To correlate sonographic and radiographic findings with patient outcomes in NEC.

Materials and methods

We reviewed sonographic and radiographic exams, as well as clinical, pathological and laboratory records. Ultrasound images were reviewed for free intraperitoneal gas, peritoneal fluid, pneumatosis intestinalis, portal gas, bowel vascularity, bowel wall thickness and echogenicity, peristalsis and the presence of dilated bowel with anechoic contents. Contemporaneously acquired radiographs were reviewed for intraperitoneal gas, pneumatosis intestinalis, portal gas, the sentinel loop sign and gas pattern. Patients were categorized into two groups based on clinical outcome.

Results

Forty-four neonates receiving 55 sonograms were included. Focal fluid collections, echogenic free fluid, increased bowel wall echogenicity and increased bowel wall thickness were statistically significant in predicting an unfavorable outcome. Other features approached significance in predicting poor outcomes: free peritoneal gas, pneumatosis intestinalis, aperistalsis, bowel wall thinning and absent bowel perfusion. Anechoic free peritoneal fluid predicted a good outcome. The sentinel loop sign on radiographs predicted an unfavorable outcome.

Conclusions

Abdominal sonography and radiography in patients with NEC can help prognosticate the outcome.

Keywords

Necrotizing enterocolitis Bowel US Neonatal 

Notes

Acknowledgments

We would like to thank Dr. J. Christopher Edgar for his assistance with the statistical calculations for this study. We are also grateful to Dr. Alan Daneman for his insight and guidance in preparing this manuscript.

Conflicts of interest

None.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Karl Muchantef
    • 1
    • 2
  • Monica Epelman
    • 1
    • 3
  • Kassa Darge
    • 1
  • Haresh Kirpalani
    • 4
  • Pablo Laje
    • 5
  • Sudha A. Anupindi
    • 1
  1. 1.Department of Radiology, The Children’s Hospital of PhiladelphiaPerelman School of Medicine at the University of PennsylvaniaPhiladelphiaUSA
  2. 2.Department of Diagnostic Radiology, Montreal Children’s HospitalMcGill UniversityMontrealCanada
  3. 3.Department of RadiologyNemours Children’s HospitalOrlandoUSA
  4. 4.Division of Neonatology, The Children’s Hospital of PhiladelphiaPerelman School of Medicine at the University of PennsylvaniaPhiladelphiaUSA
  5. 5.Department of Surgery, The Children’s Hospital of PhiladelphiaPerelman School of Medicine at the University of PennsylvaniaPhiladelphiaUSA

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