Pediatric Radiology

, Volume 43, Issue 2, pp 140–151

Rickets: Part I


DOI: 10.1007/s00247-012-2532-x

Cite this article as:
Shore, R.M. & Chesney, R.W. Pediatr Radiol (2013) 43: 140. doi:10.1007/s00247-012-2532-x


Rickets is characterized by impaired mineralization and ossification of the growth plates of growing children caused by a variety of disorders, the most frequent of which is nutritional deficiency of vitamin D. Despite ample knowledge of its etiology and the availability of cost-effective methods of preventing it, vitamin D deficiency rickets remains a significant problem in developing and developed countries. This two-part review covers the history, etiology, pathophysiology and clinical and radiographical findings of vitamin D deficiency rickets. Other less frequent causes of rickets and some of the disorders entering into the differential diagnoses of rickets are also considered. Controversial issues surrounding vitamin D deficiency include determination of what constitutes vitamin D sufficiency and the potential relationship between low levels of vitamin D metabolites in many individuals and unexplained fractures in infants.


Rickets Vitamin D Children Bone Metabolic bone disease Non-accidental trauma 

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Department of Medical Imaging, Box 9Ann & Robert H. Lurie Children’s Hospital of ChicagoChicagoUSA
  2. 2.Department of RadiologyNorthwestern University Feinberg School of MedicineChicagoUSA
  3. 3.Department of Pediatrics, Le Bonheur Children’s HospitalUniversity of Tennessee Health Science CenterMemphisUSA

Personalised recommendations